EDM25905.1 protein (Lentisphaera araneosa) - STRING interaction network

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Predicted Interactions

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Score

EDM25905.1

COG3119 Arylsulfatase A and related enzymes. (498 aa)

Predicted Functional Partners:

EDM26947.1

0.660

EDM26916.1

0.647

EDM29636.1

0.545

EDM28824.1

0.512

EDM25902.1

0.509

EDM25904.1

0.499

EDM25906.1

0.467

EDM26949.1

0.437

EDM28079.1

0.401

Your Current Organism:

Lentisphaera araneosa

NCBI taxonomy Id: 313628
Other names: L. araneosa HTCC2155, Lentisphaera araneosa HTCC2155, Lentisphaera araneosa str. HTCC2155, Lentisphaera araneosa strain HTCC2155

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDM25902.1	EDM25904.1	LNTAR_07664	LNTAR_07674	Heparan N-sulfatase; COG3119 Arylsulfatase A and related enzymes.	Hypothetical protein.	0.468
EDM25902.1	EDM25905.1	LNTAR_07664	LNTAR_07679	Heparan N-sulfatase; COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.509
EDM25902.1	EDM29636.1	LNTAR_07664	LNTAR_17838	Heparan N-sulfatase; COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.481
EDM25904.1	EDM25902.1	LNTAR_07674	LNTAR_07664	Hypothetical protein.	Heparan N-sulfatase; COG3119 Arylsulfatase A and related enzymes.	0.468
EDM25904.1	EDM25905.1	LNTAR_07674	LNTAR_07679	Hypothetical protein.	COG3119 Arylsulfatase A and related enzymes.	0.499
EDM25905.1	EDM25902.1	LNTAR_07679	LNTAR_07664	COG3119 Arylsulfatase A and related enzymes.	Heparan N-sulfatase; COG3119 Arylsulfatase A and related enzymes.	0.509
EDM25905.1	EDM25904.1	LNTAR_07679	LNTAR_07674	COG3119 Arylsulfatase A and related enzymes.	Hypothetical protein.	0.499
EDM25905.1	EDM25906.1	LNTAR_07679	LNTAR_07684	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.467
EDM25905.1	EDM26916.1	LNTAR_07679	LNTAR_06709	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.647
EDM25905.1	EDM26947.1	LNTAR_07679	LNTAR_06879	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.660
EDM25905.1	EDM26949.1	LNTAR_07679	LNTAR_06889	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.437
EDM25905.1	EDM28079.1	LNTAR_07679	LNTAR_12021	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.401
EDM25905.1	EDM28824.1	LNTAR_07679	LNTAR_09644	COG3119 Arylsulfatase A and related enzymes.	Iduronate-2-sulfatase; COG3119 Arylsulfatase A and related enzymes.	0.512
EDM25905.1	EDM29636.1	LNTAR_07679	LNTAR_17838	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.545
EDM25906.1	EDM25905.1	LNTAR_07684	LNTAR_07679	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.467
EDM26916.1	EDM25905.1	LNTAR_06709	LNTAR_07679	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.647
EDM26947.1	EDM25905.1	LNTAR_06879	LNTAR_07679	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.660
EDM26949.1	EDM25905.1	LNTAR_06889	LNTAR_07679	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.437
EDM26949.1	EDM29636.1	LNTAR_06889	LNTAR_17838	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.548
EDM28079.1	EDM25905.1	LNTAR_12021	LNTAR_07679	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.401

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006487

Protein N-linked glycosylation

10 of 65

2.52

9.43

4.95e-21

GO:0018279

Protein N-linked glycosylation via asparagine

5 of 15

2.85

5.35

9.42e-11

GO:0043686

Co-translational protein modification

3 of 4

3.21

3.27

1.18e-06

GO:0006516

Glycoprotein catabolic process

2 of 16

2.43

1.13

0.0085

GO:0043687

Post-translational protein modification

2 of 27

2.2

0.9

0.0214

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004579

Dolichyl-diphosphooligosaccharide-protein glycotransferase activity

3 of 3

3.33

2.99

3.97e-06

GO:0015095

Magnesium ion transmembrane transporter activity

2 of 12

2.55

0.99

0.0158

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008250

Oligosaccharyltransferase complex

10 of 14

3.19

14.12

1.82e-27

GO:0005789

Endoplasmic reticulum membrane

11 of 867

1.43

2.84

7.37e-14

GO:0034998

Oligosaccharyltransferase I complex

2 of 3

3.16

2.12

0.00015

GO:0016021

Integral component of membrane

11 of 5741

0.61

0.55

1.71e-05

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:38234833

(2023) Gene module reconstruction elucidates cellular differentiation processes and the regulatory logic of specialized secretion.

3 of 50

2.11

1.06

0.0101

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:8194

Oligosaccharyltransferase complex

10 of 14

3.19

14.05

2.45e-27

CL:8190

Oligosaccharyltransferase complex, and Post-translational protein targeting to membrane, translocation

11 of 30

2.9

13.68

5.03e-28

CL:8199

Oligosaccharyltransferase complex

5 of 5

3.33

6.5

1.37e-12

CL:8212

Oligosaccharyltransferase complex

2 of 5

2.93

1.43

0.0026

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

ola00513

Various types of N-glycan biosynthesis

8 of 42

2.61

8.44

6.12e-18

ola00510

N-Glycan biosynthesis

8 of 54

2.5

7.96

1.92e-17

ola04141

Protein processing in endoplasmic reticulum

9 of 170

2.06

6.03

2.03e-16

ola01100

Metabolic pathways

8 of 1552

1.04

1.18

2.04e-06

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-5663205

Infectious disease

7 of 100

2.18

4.86

1.74e-11

MAP-1643685

Disease

7 of 177

1.93

3.84

4.15e-10

MAP-446203

Asparagine N-linked glycosylation

7 of 433

1.54

2.33

1.28e-07

MAP-5223345

Miscellaneous transport and binding events

2 of 31

2.14

0.83

0.0286

MAP-597592

Post-translational protein modification

7 of 2150

0.84

0.62

0.0052

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0008250

Oligosaccharyltransferase complex

10 of 16

3.13

13.75

6.08e-27

GOCC:0005789

Endoplasmic reticulum membrane

11 of 318

1.87

5.53

2.51e-18

GOCC:0005783

Endoplasmic reticulum

11 of 610

1.59

3.67

1.47e-15

GOCC:0098796

Membrane protein complex

11 of 1010

1.37

2.54

2.90e-13

GOCC:0034998

Oligosaccharyltransferase I complex

2 of 5

2.93

1.84

0.00046

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0256

Endoplasmic reticulum

5 of 105

2.01

3.01

3.03e-07

KW-1133

Transmembrane helix

10 of 5485

0.59

0.48

0.00067

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02516

Oligosaccharyl transferase STT3 subunit

2 of 2

3.33

1.43

0.0027

PF02109

DAD family

2 of 2

3.33

1.43

0.0027

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR003674

Oligosaccharyl transferase, STT3 subunit

3 of 3

3.33

2.75

1.08e-05

IPR003038

DAD/Ost2

2 of 2

3.33

1.32

0.0042

IPR021149

Oligosaccharyl transferase complex, subunit OST3/OST6

2 of 3

3.16

1.29

0.0047

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