STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDM25074.1Thiamin-phosphate pyrophosphorylase; COG0352 Thiamine monophosphate synthase. (211 aa)    
Predicted Functional Partners:
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 
 0.985
EDM26488.1
Hypothetical protein; COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
 
 
 0.983
EDM28546.1
Isopropylmalate isomerase large subunit; COG2104 Sulfur transfer protein involved in thiamine biosynthesis.
  
 
 0.902
thiL
Thiamin-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
 
  
 0.838
EDM27081.1
COG0422 Thiamine biosynthesis protein ThiC.
 
 
 0.834
EDM24703.1
COG0422 Thiamine biosynthesis protein ThiC.
 
 
 0.833
thiH
COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes.
 
  
 0.740
EDM26669.1
COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.
  
 
 0.646
EDM28408.1
Hypothetical protein; COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes.
  
  
 0.641
EDM28205.1
Radical SAM domain protein; COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes.
  
  
 0.641
Your Current Organism:
Lentisphaera araneosa
NCBI taxonomy Id: 313628
Other names: L. araneosa HTCC2155, Lentisphaera araneosa HTCC2155, Lentisphaera araneosa str. HTCC2155, Lentisphaera araneosa strain HTCC2155
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