EDM28079.1 protein (Lentisphaera araneosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

EDM28079.1

COG3119 Arylsulfatase A and related enzymes. (458 aa)

Predicted Functional Partners:

EDM26420.1

0.716

EDM26928.1

0.605

EDM29636.1

0.602

EDM26188.1

0.597

EDM28080.1

0.572

EDM26921.1

0.570

EDM26939.1

0.521

EDM27814.1

0.484

EDM27541.1

0.463

EDM28429.1

0.420

Your Current Organism:

Lentisphaera araneosa

NCBI taxonomy Id: 313628
Other names: L. araneosa HTCC2155, Lentisphaera araneosa HTCC2155, Lentisphaera araneosa str. HTCC2155, Lentisphaera araneosa strain HTCC2155

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDM26188.1	EDM28079.1	LNTAR_16613	LNTAR_12021	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.597
EDM26188.1	EDM29636.1	LNTAR_16613	LNTAR_17838	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.455
EDM26420.1	EDM28079.1	LNTAR_05579	LNTAR_12021	Heparan N-sulfatase; COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.716
EDM26921.1	EDM28079.1	LNTAR_06734	LNTAR_12021	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.570
EDM26921.1	EDM29636.1	LNTAR_06734	LNTAR_17838	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.500
EDM26928.1	EDM28079.1	LNTAR_06769	LNTAR_12021	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.605
EDM26939.1	EDM28079.1	LNTAR_06824	LNTAR_12021	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.521
EDM27541.1	EDM28079.1	LNTAR_05496	LNTAR_12021	Heparan N-sulfatase; COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.463
EDM27541.1	EDM29636.1	LNTAR_05496	LNTAR_17838	Heparan N-sulfatase; COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.558
EDM27814.1	EDM28079.1	LNTAR_00395	LNTAR_12021	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.484
EDM28079.1	EDM26188.1	LNTAR_12021	LNTAR_16613	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.597
EDM28079.1	EDM26420.1	LNTAR_12021	LNTAR_05579	COG3119 Arylsulfatase A and related enzymes.	Heparan N-sulfatase; COG3119 Arylsulfatase A and related enzymes.	0.716
EDM28079.1	EDM26921.1	LNTAR_12021	LNTAR_06734	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.570
EDM28079.1	EDM26928.1	LNTAR_12021	LNTAR_06769	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.605
EDM28079.1	EDM26939.1	LNTAR_12021	LNTAR_06824	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.521
EDM28079.1	EDM27541.1	LNTAR_12021	LNTAR_05496	COG3119 Arylsulfatase A and related enzymes.	Heparan N-sulfatase; COG3119 Arylsulfatase A and related enzymes.	0.463
EDM28079.1	EDM27814.1	LNTAR_12021	LNTAR_00395	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.484
EDM28079.1	EDM28080.1	LNTAR_12021	LNTAR_12026	COG3119 Arylsulfatase A and related enzymes.	Hypothetical protein.	0.572
EDM28079.1	EDM28429.1	LNTAR_12021	LNTAR_10951	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.420
EDM28079.1	EDM29636.1	LNTAR_12021	LNTAR_17838	COG3119 Arylsulfatase A and related enzymes.	COG3119 Arylsulfatase A and related enzymes.	0.602

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

22

average node degree:

4

avg. local clustering coefficient:

0.809

expected number of edges:

10

PPI enrichment p-value:

0.000777

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019665

Anaerobic amino acid catabolic process

9 of 27

2.01

5.24

3.72e-14

GO:0019670

Anaerobic glutamate catabolic process

7 of 15

2.16

4.9

1.07e-11

GO:0019752

Carboxylic acid metabolic process

10 of 332

0.97

1.13

7.13e-08

GO:0019475

L-lysine catabolic process to acetate

2 of 12

1.71

0.71

0.0420

GO:1901564

Organonitrogen compound metabolic process

10 of 707

0.64

0.56

8.92e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008410

CoA-transferase activity

7 of 17

2.1

4.48

7.13e-11

GO:0016740

Transferase activity

8 of 483

0.71

0.52

0.0044

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:35757244

(2022) Regulatory Effect of Mung Bean Peptide on Prediabetic Mice Induced by High-Fat Diet.

3 of 5

2.27

2.38

2.40e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5576

Lysine degradation

11 of 20

2.23

8.17

3.71e-21

CL:5577

Coenzyme A transferase, and Beta-keto acid cleavage enzyme

7 of 12

2.25

5.45

1.32e-12

CL:5581

Coenzyme A transferase

5 of 6

2.41

4.22

4.19e-09

CL:5602

Intramolecular transferase activity, transferring amino groups, and GroES-like superfamily

2 of 5

2.09

1.0

0.0134

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

ibu00310

Lysine degradation

10 of 27

2.06

6.41

6.80e-18

ibu00640

Propanoate metabolism

7 of 40

1.73

3.25

9.58e-10

ibu00650

Butanoate metabolism

7 of 47

1.66

3.0

1.78e-09

ibu02020

Two-component system

7 of 62

1.54

2.56

8.03e-09

ibu01120

Microbial metabolism in diverse environments

7 of 155

1.14

1.35

2.29e-06

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005737

Cytoplasm

9 of 705

0.59

0.43

0.0067

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0808

Transferase

7 of 388

0.74

0.51

0.0112

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR004165

Coenzyme A transferase family I

7 of 11

2.29

5.13

1.33e-11

IPR037171

NagB/RpiA transferase-like

7 of 22

1.99

4.02

3.22e-10

IPR012792

3-oxoacid CoA-transferase, subunit A

4 of 4

2.49

3.02

1.81e-06

IPR012791

3-oxoacid CoA-transferase, subunit B

3 of 4

2.36

1.88

0.00029

IPR004164

Coenzyme A transferase active site

2 of 3

2.31

0.87

0.0248

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00882

Coenzyme A transferase

7 of 11

2.29

5.55

1.14e-12

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (24%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Fusion

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About