STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glmUN-acetylglucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (467 aa)    
Predicted Functional Partners:
glmM
Phosphomannomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
 
 0.980
murA
UDP-N-acetylglucosamine enolpyruvyl transferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
 
 
 0.957
glmS
Glucosamine 6-phosphate synthetase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 0.933
ELI_13265
COG0381 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
    
 0.930
ELI_13295
UDPglucose 6-dehydrogenase; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
  
 
 0.916
ELI_05055
Hypothetical protein; COG3178 Predicted phosphotransferase related to Ser/Thr protein kinases.
    
 0.913
prs
Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
 
  
 0.867
ELI_14205
COG0281 Malic enzyme.
  
 
 0.653
ELI_08805
Hypothetical protein; COG1403 Restriction endonuclease.
       0.619
murE
UDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
  
 0.595
Your Current Organism:
Erythrobacter litoralis
NCBI taxonomy Id: 314225
Other names: E. litoralis HTCC2594, Erythrobacter litoralis HTCC2594, Erythrobacter litoralis str. HTCC2594, Erythrobacter litoralis strain HTCC2594
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