STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAQ76938.1ProP protein; COG0477 Permeases of the major facilitator superfamily. (447 aa)    
Predicted Functional Partners:
EAQ77722.1
Ribonucleotide-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
    
  0.740
EAQ77063.1
Putative multi-domain protein.
  
     0.731
EAQ77934.1
Hypothetical protein; COG3622 Hydroxypyruvate isomerase.
 
     0.710
EAQ81244.1
Putative large multi-functional protein.
  
     0.677
EAQ77247.1
Putative large multi-functional protein.
  
     0.661
EAQ81002.1
Putative large multi-functional protein.
  
     0.636
EAQ77853.1
Probable NADH-dependent dehydrogenase; COG0673 Predicted dehydrogenases and related proteins.
 
     0.507
EAQ78946.1
Hypothetical protein.
  
  
 0.489
EAQ77753.1
Hypothetical protein.
  
     0.472
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
    
  0.470
Your Current Organism:
Blastopirellula marina
NCBI taxonomy Id: 314230
Other names: B. marina DSM 3645, Blastopirellula marina DSM 3645, Blastopirellula marina str. DSM 3645, Blastopirellula marina strain DSM 3645
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.