STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrBCOG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (319 aa)    
Predicted Functional Partners:
carA
Carbamoyl-phosphate synthase, small chain; COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family.
 
 0.999
carB
Carbamoyl-phosphate synthase (glutamine-hydrolyzing) large chain; COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family.
 
 0.999
EAQ80872.1
COG0044 Dihydroorotase and related cyclic amidohydrolases.
 0.999
EAQ78279.1
COG0044 Dihydroorotase and related cyclic amidohydrolases.
 0.999
EAQ80953.1
Dihydroorotate dehydrogenase electron transfer subunit; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.
 
 
 0.969
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.957
pyrF
COG0284 Orotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
  
 0.957
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.932
EAQ81914.1
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
 
 0.930
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate.
 
 
 0.925
Your Current Organism:
Blastopirellula marina
NCBI taxonomy Id: 314230
Other names: B. marina DSM 3645, Blastopirellula marina DSM 3645, Blastopirellula marina str. DSM 3645, Blastopirellula marina strain DSM 3645
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