STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (267 aa)    
Predicted Functional Partners:
EAQ77535.1
COG0506 Proline dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.947
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.931
EAQ79236.1
Hypothetical protein; COG3938 Proline racemase; Belongs to the proline racemase family.
    
 0.915
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.836
EAQ77685.1
COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog.
   
 
 0.615
EAQ81332.1
Hypothetical protein.
       0.562
EAQ80689.1
COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.540
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
     
 0.527
EAQ78234.1
Glutamate synthase [NADPH] large chain; COG0067 Glutamate synthase domain 1.
     
 0.523
EAQ77946.1
Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
 
  
 0.507
Your Current Organism:
Blastopirellula marina
NCBI taxonomy Id: 314230
Other names: B. marina DSM 3645, Blastopirellula marina DSM 3645, Blastopirellula marina str. DSM 3645, Blastopirellula marina strain DSM 3645
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.