| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05394.1 | ttcA | SKA53_00420 | SKA53_00425 | Hypothetical protein. | Hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.549 |
| EAQ05397.1 | ttcA | SKA53_00435 | SKA53_00425 | Hypothetical protein; COG1820 N-acetylglucosamine-6-phosphate deacetylase. | Hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.620 |
| EAQ06093.1 | EAQ07715.1 | SKA53_08306 | SKA53_12798 | COG0381 UDP-N-acetylglucosamine 2-epimerase. | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.666 |
| EAQ06093.1 | ttcA | SKA53_08306 | SKA53_00425 | COG0381 UDP-N-acetylglucosamine 2-epimerase. | Hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.614 |
| EAQ06399.1 | EAQ08212.1 | SKA53_04908 | SKA53_10819 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 0.700 |
| EAQ06399.1 | guaA | SKA53_04908 | SKA53_04933 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.943 |
| EAQ06399.1 | ttcA | SKA53_04908 | SKA53_00425 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.552 |
| EAQ07715.1 | EAQ06093.1 | SKA53_12798 | SKA53_08306 | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | COG0381 UDP-N-acetylglucosamine 2-epimerase. | 0.666 |
| EAQ07715.1 | ttcA | SKA53_12798 | SKA53_00425 | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.771 |
| EAQ08212.1 | EAQ06399.1 | SKA53_10819 | SKA53_04908 | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.700 |
| EAQ08212.1 | guaA | SKA53_10819 | SKA53_04933 | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.964 |
| EAQ08212.1 | rpoC | SKA53_10819 | SKA53_13278 | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.697 |
| EAQ08212.1 | ttcA | SKA53_10819 | SKA53_00425 | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | Hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.854 |
| guaA | EAQ06399.1 | SKA53_04933 | SKA53_04908 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.943 |
| guaA | EAQ08212.1 | SKA53_04933 | SKA53_10819 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 0.964 |
| guaA | pth | SKA53_04933 | SKA53_01241 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.610 |
| guaA | rpoC | SKA53_04933 | SKA53_13278 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.959 |
| guaA | ttcA | SKA53_04933 | SKA53_00425 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.868 |
| mfd | pth | SKA53_04658 | SKA53_01241 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.720 |
| mfd | rpoC | SKA53_04658 | SKA53_13278 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.980 |