| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05231.1 | EAQ05539.1 | SKA53_05630 | SKA53_00594 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Hypothetical protein; COG0282 Acetate kinase. | 0.916 |
| EAQ05231.1 | EAQ05601.1 | SKA53_05630 | SKA53_00904 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG1042 Acyl-CoA synthetase (NDP forming). | 0.845 |
| EAQ05231.1 | EAQ07520.1 | SKA53_05630 | SKA53_11823 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.988 |
| EAQ05231.1 | EAQ07926.1 | SKA53_05630 | SKA53_09389 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.988 |
| EAQ05231.1 | EAQ07928.1 | SKA53_05630 | SKA53_09399 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | propionate--CoA ligase; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | 0.896 |
| EAQ05231.1 | acsA | SKA53_05630 | SKA53_10704 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.896 |
| EAQ05231.1 | glcB | SKA53_05630 | SKA53_07132 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.558 |
| EAQ05538.1 | EAQ05539.1 | SKA53_00589 | SKA53_00594 | Oxidoreductase, molybdopterin-binding; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Hypothetical protein; COG0282 Acetate kinase. | 0.811 |
| EAQ05538.1 | EAQ05540.1 | SKA53_00589 | SKA53_00599 | Oxidoreductase, molybdopterin-binding; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Hypothetical protein; COG0477 Permeases of the major facilitator superfamily. | 0.816 |
| EAQ05538.1 | EAQ05541.1 | SKA53_00589 | SKA53_00604 | Oxidoreductase, molybdopterin-binding; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. | 0.847 |
| EAQ05538.1 | EAQ07520.1 | SKA53_00589 | SKA53_11823 | Oxidoreductase, molybdopterin-binding; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.828 |
| EAQ05538.1 | EAQ07926.1 | SKA53_00589 | SKA53_09389 | Oxidoreductase, molybdopterin-binding; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.828 |
| EAQ05538.1 | glcB | SKA53_00589 | SKA53_07132 | Oxidoreductase, molybdopterin-binding; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.483 |
| EAQ05539.1 | EAQ05231.1 | SKA53_00594 | SKA53_05630 | Hypothetical protein; COG0282 Acetate kinase. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.916 |
| EAQ05539.1 | EAQ05538.1 | SKA53_00594 | SKA53_00589 | Hypothetical protein; COG0282 Acetate kinase. | Oxidoreductase, molybdopterin-binding; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.811 |
| EAQ05539.1 | EAQ05540.1 | SKA53_00594 | SKA53_00599 | Hypothetical protein; COG0282 Acetate kinase. | Hypothetical protein; COG0477 Permeases of the major facilitator superfamily. | 0.820 |
| EAQ05539.1 | EAQ05541.1 | SKA53_00594 | SKA53_00604 | Hypothetical protein; COG0282 Acetate kinase. | COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. | 0.818 |
| EAQ05539.1 | EAQ05601.1 | SKA53_00594 | SKA53_00904 | Hypothetical protein; COG0282 Acetate kinase. | COG1042 Acyl-CoA synthetase (NDP forming). | 0.856 |
| EAQ05539.1 | EAQ07520.1 | SKA53_00594 | SKA53_11823 | Hypothetical protein; COG0282 Acetate kinase. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.949 |
| EAQ05539.1 | EAQ07926.1 | SKA53_00594 | SKA53_09389 | Hypothetical protein; COG0282 Acetate kinase. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.949 |