| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05231.1 | EAQ05539.1 | SKA53_05630 | SKA53_00594 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Hypothetical protein; COG0282 Acetate kinase. | 0.701 |
| EAQ05231.1 | EAQ05601.1 | SKA53_05630 | SKA53_00904 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG1042 Acyl-CoA synthetase (NDP forming). | 0.880 |
| EAQ05231.1 | EAQ05602.1 | SKA53_05630 | SKA53_00909 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG1960 Acyl-CoA dehydrogenases. | 0.420 |
| EAQ05231.1 | EAQ07315.1 | SKA53_05630 | SKA53_02926 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.921 |
| EAQ05231.1 | EAQ07520.1 | SKA53_05630 | SKA53_11823 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.994 |
| EAQ05231.1 | EAQ07916.1 | SKA53_05630 | SKA53_09339 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase. | 0.853 |
| EAQ05231.1 | EAQ07926.1 | SKA53_05630 | SKA53_09389 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.994 |
| EAQ05231.1 | sucC | SKA53_05630 | SKA53_14531 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.983 |
| EAQ05231.1 | sucD | SKA53_05630 | SKA53_14526 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.957 |
| EAQ05539.1 | EAQ05231.1 | SKA53_00594 | SKA53_05630 | Hypothetical protein; COG0282 Acetate kinase. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.701 |
| EAQ05539.1 | EAQ05601.1 | SKA53_00594 | SKA53_00904 | Hypothetical protein; COG0282 Acetate kinase. | COG1042 Acyl-CoA synthetase (NDP forming). | 0.884 |
| EAQ05539.1 | EAQ07315.1 | SKA53_00594 | SKA53_02926 | Hypothetical protein; COG0282 Acetate kinase. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.731 |
| EAQ05539.1 | EAQ07520.1 | SKA53_00594 | SKA53_11823 | Hypothetical protein; COG0282 Acetate kinase. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.954 |
| EAQ05539.1 | EAQ07916.1 | SKA53_00594 | SKA53_09339 | Hypothetical protein; COG0282 Acetate kinase. | enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase. | 0.531 |
| EAQ05539.1 | EAQ07926.1 | SKA53_00594 | SKA53_09389 | Hypothetical protein; COG0282 Acetate kinase. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.954 |
| EAQ05539.1 | sucC | SKA53_00594 | SKA53_14531 | Hypothetical protein; COG0282 Acetate kinase. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.638 |
| EAQ05539.1 | sucD | SKA53_00594 | SKA53_14526 | Hypothetical protein; COG0282 Acetate kinase. | Succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.547 |
| EAQ05600.1 | EAQ05601.1 | SKA53_00899 | SKA53_00904 | carnitinyl-CoA dehydratase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | COG1042 Acyl-CoA synthetase (NDP forming). | 0.945 |
| EAQ05600.1 | EAQ05602.1 | SKA53_00899 | SKA53_00909 | carnitinyl-CoA dehydratase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | COG1960 Acyl-CoA dehydrogenases. | 0.945 |
| EAQ05600.1 | EAQ07916.1 | SKA53_00899 | SKA53_09339 | carnitinyl-CoA dehydratase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase. | 0.631 |