| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05402.1 | EAQ05600.1 | SKA53_00460 | SKA53_00899 | Beta-ketothiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | carnitinyl-CoA dehydratase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.679 |
| EAQ05402.1 | EAQ05602.1 | SKA53_00460 | SKA53_00909 | Beta-ketothiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | COG1960 Acyl-CoA dehydrogenases. | 0.606 |
| EAQ05402.1 | EAQ07916.1 | SKA53_00460 | SKA53_09339 | Beta-ketothiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase. | 0.999 |
| EAQ05402.1 | EAQ07928.1 | SKA53_00460 | SKA53_09399 | Beta-ketothiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | propionate--CoA ligase; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | 0.695 |
| EAQ05402.1 | acsA | SKA53_00460 | SKA53_10704 | Beta-ketothiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.695 |
| EAQ05402.1 | lcdH | SKA53_00460 | SKA53_00914 | Beta-ketothiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxybutyryl-CoA dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine. | 0.897 |
| EAQ05600.1 | EAQ05402.1 | SKA53_00899 | SKA53_00460 | carnitinyl-CoA dehydratase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | Beta-ketothiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.679 |
| EAQ05600.1 | EAQ05602.1 | SKA53_00899 | SKA53_00909 | carnitinyl-CoA dehydratase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | COG1960 Acyl-CoA dehydrogenases. | 0.945 |
| EAQ05600.1 | EAQ05604.1 | SKA53_00899 | SKA53_00919 | carnitinyl-CoA dehydratase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | Hypothetical protein. | 0.515 |
| EAQ05600.1 | EAQ06617.1 | SKA53_00899 | SKA53_13756 | carnitinyl-CoA dehydratase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.679 |
| EAQ05600.1 | EAQ07915.1 | SKA53_00899 | SKA53_09334 | carnitinyl-CoA dehydratase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.679 |
| EAQ05600.1 | EAQ07916.1 | SKA53_00899 | SKA53_09339 | carnitinyl-CoA dehydratase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase. | 0.631 |
| EAQ05600.1 | EAQ08086.1 | SKA53_00899 | SKA53_10189 | carnitinyl-CoA dehydratase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.679 |
| EAQ05600.1 | lcdH | SKA53_00899 | SKA53_00914 | carnitinyl-CoA dehydratase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | 3-hydroxybutyryl-CoA dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine. | 0.935 |
| EAQ05602.1 | EAQ05402.1 | SKA53_00909 | SKA53_00460 | COG1960 Acyl-CoA dehydrogenases. | Beta-ketothiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.606 |
| EAQ05602.1 | EAQ05600.1 | SKA53_00909 | SKA53_00899 | COG1960 Acyl-CoA dehydrogenases. | carnitinyl-CoA dehydratase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.945 |
| EAQ05602.1 | EAQ05604.1 | SKA53_00909 | SKA53_00919 | COG1960 Acyl-CoA dehydrogenases. | Hypothetical protein. | 0.820 |
| EAQ05602.1 | EAQ06617.1 | SKA53_00909 | SKA53_13756 | COG1960 Acyl-CoA dehydrogenases. | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.863 |
| EAQ05602.1 | EAQ07915.1 | SKA53_00909 | SKA53_09334 | COG1960 Acyl-CoA dehydrogenases. | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.863 |
| EAQ05602.1 | EAQ07916.1 | SKA53_00909 | SKA53_09339 | COG1960 Acyl-CoA dehydrogenases. | enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase. | 0.976 |