| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ07335.1 | trpA | SKA53_03026 | SKA53_01266 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.988 |
| EAQ07335.1 | trpB | SKA53_03026 | SKA53_01211 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.992 |
| EAQ07335.1 | trpC | SKA53_03026 | SKA53_03011 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.999 |
| EAQ07335.1 | trpD | SKA53_03026 | SKA53_03021 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
| EAQ07335.1 | trpE | SKA53_03026 | SKA53_03036 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.999 |
| EAQ07335.1 | trpF | SKA53_03026 | SKA53_01206 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | COG0135 Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.994 |
| EAQ07857.1 | EAQ08105.1 | SKA53_09044 | SKA53_10284 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | COG0560 Phosphoserine phosphatase. | 0.413 |
| EAQ07857.1 | trpA | SKA53_09044 | SKA53_01266 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.891 |
| EAQ07857.1 | trpB | SKA53_09044 | SKA53_01211 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.891 |
| EAQ08105.1 | EAQ07857.1 | SKA53_10284 | SKA53_09044 | COG0560 Phosphoserine phosphatase. | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | 0.413 |
| EAQ08105.1 | trpA | SKA53_10284 | SKA53_01266 | COG0560 Phosphoserine phosphatase. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.853 |
| EAQ08105.1 | trpB | SKA53_10284 | SKA53_01211 | COG0560 Phosphoserine phosphatase. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.878 |
| lgt | trpA | SKA53_01801 | SKA53_01266 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.885 |
| lgt | trpB | SKA53_01801 | SKA53_01211 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.884 |
| metAA | trpB | SKA53_04518 | SKA53_01211 | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.872 |
| metAA | trpF | SKA53_04518 | SKA53_01206 | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | COG0135 Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.519 |
| trpA | EAQ07335.1 | SKA53_01266 | SKA53_03026 | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | COG0512 Anthranilate/para-aminobenzoate synthases component II. | 0.988 |
| trpA | EAQ07857.1 | SKA53_01266 | SKA53_09044 | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | 0.891 |
| trpA | EAQ08105.1 | SKA53_01266 | SKA53_10284 | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | COG0560 Phosphoserine phosphatase. | 0.853 |
| trpA | lgt | SKA53_01266 | SKA53_01801 | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.885 |