| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05233.1 | trpA | SKA53_05640 | SKA53_01266 | COG1045 Serine acetyltransferase. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.820 |
| EAQ05233.1 | trpB | SKA53_05640 | SKA53_01211 | COG1045 Serine acetyltransferase. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.818 |
| EAQ05233.1 | trpC | SKA53_05640 | SKA53_03011 | COG1045 Serine acetyltransferase. | COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.669 |
| EAQ05233.1 | trpF | SKA53_05640 | SKA53_01206 | COG1045 Serine acetyltransferase. | COG0135 Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.541 |
| EAQ07335.1 | aroC | SKA53_03026 | SKA53_12153 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.934 |
| EAQ07335.1 | trpA | SKA53_03026 | SKA53_01266 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.986 |
| EAQ07335.1 | trpB | SKA53_03026 | SKA53_01211 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.986 |
| EAQ07335.1 | trpC | SKA53_03026 | SKA53_03011 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.999 |
| EAQ07335.1 | trpD | SKA53_03026 | SKA53_03021 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
| EAQ07335.1 | trpE | SKA53_03026 | SKA53_03036 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.999 |
| EAQ07335.1 | trpF | SKA53_03026 | SKA53_01206 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | COG0135 Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.991 |
| EAQ07857.1 | aroC | SKA53_09044 | SKA53_12153 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.407 |
| EAQ07857.1 | trpA | SKA53_09044 | SKA53_01266 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.870 |
| EAQ07857.1 | trpB | SKA53_09044 | SKA53_01211 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.862 |
| aroC | EAQ07335.1 | SKA53_12153 | SKA53_03026 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | COG0512 Anthranilate/para-aminobenzoate synthases component II. | 0.934 |
| aroC | EAQ07857.1 | SKA53_12153 | SKA53_09044 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | 0.407 |
| aroC | trpA | SKA53_12153 | SKA53_01266 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.833 |
| aroC | trpB | SKA53_12153 | SKA53_01211 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.660 |
| aroC | trpC | SKA53_12153 | SKA53_03011 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.735 |
| aroC | trpD | SKA53_12153 | SKA53_03021 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.947 |
