| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ06260.1 | EAQ07002.1 | SKA53_04213 | SKA53_01361 | Metallo-beta-lactamase family protein; COG0491 Zn-dependent hydrolases, including glyoxylases. | Hydrolase, NUDIX family; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.643 |
| EAQ06457.1 | EAQ07002.1 | SKA53_05198 | SKA53_01361 | DEAD-box protein, ATP-independent RNA helicase; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | Hydrolase, NUDIX family; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.534 |
| EAQ06457.1 | rnr | SKA53_05198 | SKA53_10249 | DEAD-box protein, ATP-independent RNA helicase; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.536 |
| EAQ06946.1 | EAQ07002.1 | SKA53_15401 | SKA53_01361 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Hydrolase, NUDIX family; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.534 |
| EAQ06946.1 | EAQ07715.1 | SKA53_15401 | SKA53_12798 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.773 |
| EAQ07002.1 | EAQ06260.1 | SKA53_01361 | SKA53_04213 | Hydrolase, NUDIX family; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Metallo-beta-lactamase family protein; COG0491 Zn-dependent hydrolases, including glyoxylases. | 0.643 |
| EAQ07002.1 | EAQ06457.1 | SKA53_01361 | SKA53_05198 | Hydrolase, NUDIX family; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | DEAD-box protein, ATP-independent RNA helicase; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | 0.534 |
| EAQ07002.1 | EAQ06946.1 | SKA53_01361 | SKA53_15401 | Hydrolase, NUDIX family; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.534 |
| EAQ07002.1 | EAQ07003.1 | SKA53_01361 | SKA53_01366 | Hydrolase, NUDIX family; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Hypothetical protein; COG1405 Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB. | 0.889 |
| EAQ07002.1 | EAQ07005.1 | SKA53_01361 | SKA53_01376 | Hydrolase, NUDIX family; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Sigma-24; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. | 0.588 |
| EAQ07002.1 | EAQ07006.1 | SKA53_01361 | SKA53_01381 | Hydrolase, NUDIX family; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Hypothetical protein. | 0.514 |
| EAQ07002.1 | EAQ07715.1 | SKA53_01361 | SKA53_12798 | Hydrolase, NUDIX family; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.782 |
| EAQ07002.1 | nadE | SKA53_01361 | SKA53_08994 | Hydrolase, NUDIX family; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.756 |
| EAQ07002.1 | ribB | SKA53_01361 | SKA53_01971 | Hydrolase, NUDIX family; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.789 |
| EAQ07002.1 | rnr | SKA53_01361 | SKA53_10249 | Hydrolase, NUDIX family; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.634 |
| EAQ07003.1 | EAQ07002.1 | SKA53_01366 | SKA53_01361 | Hypothetical protein; COG1405 Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB. | Hydrolase, NUDIX family; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.889 |
| EAQ07003.1 | EAQ07005.1 | SKA53_01366 | SKA53_01376 | Hypothetical protein; COG1405 Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB. | Sigma-24; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. | 0.597 |
| EAQ07003.1 | EAQ07006.1 | SKA53_01366 | SKA53_01381 | Hypothetical protein; COG1405 Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB. | Hypothetical protein. | 0.537 |
| EAQ07005.1 | EAQ07002.1 | SKA53_01376 | SKA53_01361 | Sigma-24; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. | Hydrolase, NUDIX family; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.588 |
| EAQ07005.1 | EAQ07003.1 | SKA53_01376 | SKA53_01366 | Sigma-24; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. | Hypothetical protein; COG1405 Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB. | 0.597 |