| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05758.1 | EAQ06790.1 | SKA53_06627 | SKA53_14621 | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.916 |
| EAQ05758.1 | EAQ07066.1 | SKA53_06627 | SKA53_01681 | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.916 |
| EAQ05758.1 | EAQ07315.1 | SKA53_06627 | SKA53_02926 | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.784 |
| EAQ05758.1 | EAQ07964.1 | SKA53_06627 | SKA53_09579 | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | methylmalonyl-CoA epimerase; COG0346 Lactoylglutathione lyase and related lyases. | 0.459 |
| EAQ05758.1 | mdh | SKA53_06627 | SKA53_14541 | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.446 |
| EAQ05758.1 | sucC | SKA53_06627 | SKA53_14531 | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.528 |
| EAQ05758.1 | sucD | SKA53_06627 | SKA53_14526 | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | Succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.480 |
| EAQ05902.1 | EAQ06790.1 | SKA53_07351 | SKA53_14621 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.893 |
| EAQ05902.1 | EAQ07066.1 | SKA53_07351 | SKA53_01681 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.928 |
| EAQ05902.1 | EAQ07315.1 | SKA53_07351 | SKA53_02926 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.890 |
| EAQ05902.1 | mdh | SKA53_07351 | SKA53_14541 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.924 |
| EAQ05902.1 | pckA | SKA53_07351 | SKA53_13138 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.916 |
| EAQ05902.1 | sucC | SKA53_07351 | SKA53_14531 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.905 |
| EAQ05902.1 | sucD | SKA53_07351 | SKA53_14526 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.887 |
| EAQ06790.1 | EAQ05758.1 | SKA53_14621 | SKA53_06627 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. | 0.916 |
| EAQ06790.1 | EAQ05902.1 | SKA53_14621 | SKA53_07351 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.893 |
| EAQ06790.1 | EAQ07066.1 | SKA53_14621 | SKA53_01681 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.999 |
| EAQ06790.1 | EAQ07315.1 | SKA53_14621 | SKA53_02926 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.926 |
| EAQ06790.1 | EAQ07940.1 | SKA53_14621 | SKA53_09459 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | ATPase; COG1703 putative periplasmic protein kinase ArgK and related GTPases of G3E family. | 0.983 |
| EAQ06790.1 | EAQ07964.1 | SKA53_14621 | SKA53_09579 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | methylmalonyl-CoA epimerase; COG0346 Lactoylglutathione lyase and related lyases. | 0.978 |