Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EAQ07066.1COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. (708 aa)    
Predicted Functional Partners:
EAQ07940.1
ATPase; COG1703 putative periplasmic protein kinase ArgK and related GTPases of G3E family.
 0.999
EAQ06790.1
COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit.
 
0.998
EAQ07964.1
methylmalonyl-CoA epimerase; COG0346 Lactoylglutathione lyase and related lyases.
 
  
 0.988
sucD
Succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.922
EAQ05758.1
Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases.
  
 
 0.918
EAQ05902.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
    
 0.916
EAQ07315.1
COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
    
 0.904
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.898
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
    
 0.891
EAQ07326.1
COG0372 Citrate synthase; Belongs to the citrate synthase family.
     
 0.886
Your Current Organism:
Yoonia vestfoldensis SKA53
NCBI taxonomy Id: 314232
Other names: Loktanella vestfoldensis SKA53, Y. vestfoldensis SKA53
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