| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05392.1 | EAQ07071.1 | SKA53_00410 | SKA53_01706 | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | 0.560 |
| EAQ05392.1 | EAQ08157.1 | SKA53_00410 | SKA53_10544 | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.602 |
| EAQ05392.1 | dnaA | SKA53_00410 | SKA53_10549 | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.685 |
| EAQ05392.1 | pheT-2 | SKA53_00410 | SKA53_10114 | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | phenylalanyl-tRNA synthetase, beta subunit; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.414 |
| EAQ05392.1 | recF | SKA53_00410 | SKA53_10539 | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | Recombination protein F; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.621 |
| EAQ07069.1 | EAQ07071.1 | SKA53_01696 | SKA53_01706 | Phosphatase, Ppx/GppA family; COG0248 Exopolyphosphatase. | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | 0.699 |
| EAQ07069.1 | EAQ07072.1 | SKA53_01696 | SKA53_01711 | Phosphatase, Ppx/GppA family; COG0248 Exopolyphosphatase. | Lipocalin-related protein and Bos/Can/Equ allergen; COG0628 Predicted permease. | 0.699 |
| EAQ07069.1 | ppk | SKA53_01696 | SKA53_01701 | Phosphatase, Ppx/GppA family; COG0248 Exopolyphosphatase. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.938 |
| EAQ07069.1 | proS | SKA53_01696 | SKA53_01716 | Phosphatase, Ppx/GppA family; COG0248 Exopolyphosphatase. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. | 0.567 |
| EAQ07071.1 | EAQ05392.1 | SKA53_01706 | SKA53_00410 | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.560 |
| EAQ07071.1 | EAQ07069.1 | SKA53_01706 | SKA53_01696 | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | Phosphatase, Ppx/GppA family; COG0248 Exopolyphosphatase. | 0.699 |
| EAQ07071.1 | EAQ07072.1 | SKA53_01706 | SKA53_01711 | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | Lipocalin-related protein and Bos/Can/Equ allergen; COG0628 Predicted permease. | 0.943 |
| EAQ07071.1 | EAQ07249.1 | SKA53_01706 | SKA53_02596 | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.777 |
| EAQ07071.1 | EAQ08157.1 | SKA53_01706 | SKA53_10544 | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.975 |
| EAQ07071.1 | dnaA | SKA53_01706 | SKA53_10549 | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.682 |
| EAQ07071.1 | pheT-2 | SKA53_01706 | SKA53_10114 | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | phenylalanyl-tRNA synthetase, beta subunit; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.496 |
| EAQ07071.1 | ppk | SKA53_01706 | SKA53_01701 | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.784 |
| EAQ07071.1 | proS | SKA53_01706 | SKA53_01716 | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. | 0.700 |
| EAQ07071.1 | recF | SKA53_01706 | SKA53_10539 | Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. | Recombination protein F; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.653 |
| EAQ07072.1 | EAQ07069.1 | SKA53_01711 | SKA53_01696 | Lipocalin-related protein and Bos/Can/Equ allergen; COG0628 Predicted permease. | Phosphatase, Ppx/GppA family; COG0248 Exopolyphosphatase. | 0.699 |