| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05812.1 | EAQ07123.1 | SKA53_06897 | SKA53_01966 | COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family. | COG0307 Riboflavin synthase alpha chain. | 0.828 |
| EAQ05812.1 | EAQ07733.1 | SKA53_06897 | SKA53_12888 | COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family. | Riboflavin biosynthesis protein RibF; COG0196 FAD synthase; Belongs to the ribF family. | 0.860 |
| EAQ06859.1 | EAQ07123.1 | SKA53_14966 | SKA53_01966 | COG0254 Ribosomal protein L31; Belongs to the bacterial ribosomal protein bL31 family. | COG0307 Riboflavin synthase alpha chain. | 0.764 |
| EAQ06859.1 | EAQ08022.1 | SKA53_14966 | SKA53_09869 | COG0254 Ribosomal protein L31; Belongs to the bacterial ribosomal protein bL31 family. | COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. | 0.609 |
| EAQ06859.1 | ribB | SKA53_14966 | SKA53_01971 | COG0254 Ribosomal protein L31; Belongs to the bacterial ribosomal protein bL31 family. | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.528 |
| EAQ07119.1 | EAQ07123.1 | SKA53_01946 | SKA53_01966 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | COG0307 Riboflavin synthase alpha chain. | 0.999 |
| EAQ07119.1 | EAQ07733.1 | SKA53_01946 | SKA53_12888 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin biosynthesis protein RibF; COG0196 FAD synthase; Belongs to the ribF family. | 0.774 |
| EAQ07119.1 | nusB | SKA53_01946 | SKA53_01981 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Putative N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.748 |
| EAQ07119.1 | ribA | SKA53_01946 | SKA53_10264 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.998 |
| EAQ07119.1 | ribB | SKA53_01946 | SKA53_01971 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.999 |
| EAQ07119.1 | ribH | SKA53_01946 | SKA53_01976 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin synthase, beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.998 |
| EAQ07122.1 | EAQ07123.1 | SKA53_01961 | SKA53_01966 | COG3562 Capsule polysaccharide export protein. | COG0307 Riboflavin synthase alpha chain. | 0.701 |
| EAQ07122.1 | nusB | SKA53_01961 | SKA53_01981 | COG3562 Capsule polysaccharide export protein. | Putative N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.516 |
| EAQ07122.1 | ribB | SKA53_01961 | SKA53_01971 | COG3562 Capsule polysaccharide export protein. | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.515 |
| EAQ07122.1 | ribH | SKA53_01961 | SKA53_01976 | COG3562 Capsule polysaccharide export protein. | Riboflavin synthase, beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.516 |
| EAQ07123.1 | EAQ05812.1 | SKA53_01966 | SKA53_06897 | COG0307 Riboflavin synthase alpha chain. | COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family. | 0.828 |
| EAQ07123.1 | EAQ06859.1 | SKA53_01966 | SKA53_14966 | COG0307 Riboflavin synthase alpha chain. | COG0254 Ribosomal protein L31; Belongs to the bacterial ribosomal protein bL31 family. | 0.764 |
| EAQ07123.1 | EAQ07119.1 | SKA53_01966 | SKA53_01946 | COG0307 Riboflavin synthase alpha chain. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
| EAQ07123.1 | EAQ07122.1 | SKA53_01966 | SKA53_01961 | COG0307 Riboflavin synthase alpha chain. | COG3562 Capsule polysaccharide export protein. | 0.701 |
| EAQ07123.1 | EAQ07733.1 | SKA53_01966 | SKA53_12888 | COG0307 Riboflavin synthase alpha chain. | Riboflavin biosynthesis protein RibF; COG0196 FAD synthase; Belongs to the ribF family. | 0.957 |