| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05233.1 | EAQ05459.1 | SKA53_05640 | SKA53_03584 | COG1045 Serine acetyltransferase. | COG0031 Cysteine synthase. | 0.996 |
| EAQ05233.1 | EAQ05916.1 | SKA53_05640 | SKA53_07421 | COG1045 Serine acetyltransferase. | COG2873 O-acetylhomoserine sulfhydrylase. | 0.685 |
| EAQ05233.1 | EAQ06946.1 | SKA53_05640 | SKA53_15401 | COG1045 Serine acetyltransferase. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.702 |
| EAQ05233.1 | EAQ07104.1 | SKA53_05640 | SKA53_01871 | COG1045 Serine acetyltransferase. | COG0460 Homoserine dehydrogenase. | 0.865 |
| EAQ05233.1 | EAQ07264.1 | SKA53_05640 | SKA53_02671 | COG1045 Serine acetyltransferase. | COG0155 Sulfite reductase, beta subunit (hemoprotein). | 0.464 |
| EAQ05233.1 | metZ | SKA53_05640 | SKA53_02111 | COG1045 Serine acetyltransferase. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.863 |
| EAQ05427.1 | EAQ05459.1 | SKA53_03424 | SKA53_03584 | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | COG0031 Cysteine synthase. | 0.877 |
| EAQ05427.1 | EAQ05916.1 | SKA53_03424 | SKA53_07421 | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | COG2873 O-acetylhomoserine sulfhydrylase. | 0.937 |
| EAQ05427.1 | EAQ06946.1 | SKA53_03424 | SKA53_15401 | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.926 |
| EAQ05427.1 | EAQ07104.1 | SKA53_03424 | SKA53_01871 | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | COG0460 Homoserine dehydrogenase. | 0.889 |
| EAQ05427.1 | EAQ08046.1 | SKA53_03424 | SKA53_09989 | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | Aminotransferase, classes I and II; COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities. | 0.922 |
| EAQ05427.1 | metK | SKA53_03424 | SKA53_01171 | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.939 |
| EAQ05427.1 | metZ | SKA53_03424 | SKA53_02111 | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.853 |
| EAQ05459.1 | EAQ05233.1 | SKA53_03584 | SKA53_05640 | COG0031 Cysteine synthase. | COG1045 Serine acetyltransferase. | 0.996 |
| EAQ05459.1 | EAQ05427.1 | SKA53_03584 | SKA53_03424 | COG0031 Cysteine synthase. | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | 0.877 |
| EAQ05459.1 | EAQ05916.1 | SKA53_03584 | SKA53_07421 | COG0031 Cysteine synthase. | COG2873 O-acetylhomoserine sulfhydrylase. | 0.936 |
| EAQ05459.1 | EAQ06946.1 | SKA53_03584 | SKA53_15401 | COG0031 Cysteine synthase. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.928 |
| EAQ05459.1 | EAQ07104.1 | SKA53_03584 | SKA53_01871 | COG0031 Cysteine synthase. | COG0460 Homoserine dehydrogenase. | 0.613 |
| EAQ05459.1 | EAQ07264.1 | SKA53_03584 | SKA53_02671 | COG0031 Cysteine synthase. | COG0155 Sulfite reductase, beta subunit (hemoprotein). | 0.958 |
| EAQ05459.1 | EAQ08046.1 | SKA53_03584 | SKA53_09989 | COG0031 Cysteine synthase. | Aminotransferase, classes I and II; COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities. | 0.904 |