| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05846.1 | folE2 | SKA53_07067 | SKA53_02116 | Dihydroneopterin aldolase, putative; COG1539 Dihydroneopterin aldolase. | Hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.827 |
| EAQ05846.1 | ribB | SKA53_07067 | SKA53_01971 | Dihydroneopterin aldolase, putative; COG1539 Dihydroneopterin aldolase. | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.461 |
| EAQ06061.1 | EAQ06479.1 | SKA53_08146 | SKA53_05308 | Hypothetical protein; COG0642 Signal transduction histidine kinase. | mazG family protein; COG1694 Predicted pyrophosphatase. | 0.883 |
| EAQ06061.1 | EAQ06517.1 | SKA53_08146 | SKA53_05498 | Hypothetical protein; COG0642 Signal transduction histidine kinase. | COG0840 Methyl-accepting chemotaxis protein. | 0.984 |
| EAQ06061.1 | EAQ06858.1 | SKA53_08146 | SKA53_14961 | Hypothetical protein; COG0642 Signal transduction histidine kinase. | Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein. | 0.984 |
| EAQ06061.1 | EAQ07771.1 | SKA53_08146 | SKA53_13078 | Hypothetical protein; COG0642 Signal transduction histidine kinase. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.928 |
| EAQ06061.1 | folE2 | SKA53_08146 | SKA53_02116 | Hypothetical protein; COG0642 Signal transduction histidine kinase. | Hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.744 |
| EAQ06061.1 | moaA | SKA53_08146 | SKA53_06252 | Hypothetical protein; COG0642 Signal transduction histidine kinase. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.833 |
| EAQ06061.1 | ndk | SKA53_08146 | SKA53_05208 | Hypothetical protein; COG0642 Signal transduction histidine kinase. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.858 |
| EAQ06061.1 | ribA | SKA53_08146 | SKA53_10264 | Hypothetical protein; COG0642 Signal transduction histidine kinase. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.832 |
| EAQ06061.1 | ribB | SKA53_08146 | SKA53_01971 | Hypothetical protein; COG0642 Signal transduction histidine kinase. | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.876 |
| EAQ06479.1 | EAQ06061.1 | SKA53_05308 | SKA53_08146 | mazG family protein; COG1694 Predicted pyrophosphatase. | Hypothetical protein; COG0642 Signal transduction histidine kinase. | 0.883 |
| EAQ06479.1 | EAQ06517.1 | SKA53_05308 | SKA53_05498 | mazG family protein; COG1694 Predicted pyrophosphatase. | COG0840 Methyl-accepting chemotaxis protein. | 0.786 |
| EAQ06479.1 | EAQ06858.1 | SKA53_05308 | SKA53_14961 | mazG family protein; COG1694 Predicted pyrophosphatase. | Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein. | 0.786 |
| EAQ06479.1 | EAQ07771.1 | SKA53_05308 | SKA53_13078 | mazG family protein; COG1694 Predicted pyrophosphatase. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.876 |
| EAQ06479.1 | folE2 | SKA53_05308 | SKA53_02116 | mazG family protein; COG1694 Predicted pyrophosphatase. | Hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.815 |
| EAQ06479.1 | moaA | SKA53_05308 | SKA53_06252 | mazG family protein; COG1694 Predicted pyrophosphatase. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.819 |
| EAQ06479.1 | ndk | SKA53_05308 | SKA53_05208 | mazG family protein; COG1694 Predicted pyrophosphatase. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.815 |
| EAQ06479.1 | ribA | SKA53_05308 | SKA53_10264 | mazG family protein; COG1694 Predicted pyrophosphatase. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.815 |
| EAQ06479.1 | ribB | SKA53_05308 | SKA53_01971 | mazG family protein; COG1694 Predicted pyrophosphatase. | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.846 |