| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ06946.1 | EAQ07520.1 | SKA53_15401 | SKA53_11823 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.434 |
| EAQ06946.1 | EAQ07926.1 | SKA53_15401 | SKA53_09389 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.434 |
| EAQ06946.1 | fhs | SKA53_15401 | SKA53_08541 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Formate--tetrahydrofolate ligase; COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | 0.959 |
| EAQ06946.1 | folD | SKA53_15401 | SKA53_08536 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | folD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.774 |
| EAQ06946.1 | purU | SKA53_15401 | SKA53_02306 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.746 |
| EAQ07148.1 | EAQ07520.1 | SKA53_02091 | SKA53_11823 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.913 |
| EAQ07148.1 | EAQ07926.1 | SKA53_02091 | SKA53_09389 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.913 |
| EAQ07148.1 | fhs | SKA53_02091 | SKA53_08541 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | Formate--tetrahydrofolate ligase; COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | 0.588 |
| EAQ07148.1 | folD | SKA53_02091 | SKA53_08536 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | folD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.493 |
| EAQ07148.1 | purU | SKA53_02091 | SKA53_02306 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.729 |
| EAQ07192.1 | EAQ07193.1 | SKA53_02311 | SKA53_02316 | 5-dehydro-2-deoxygluconokinase; COG0524 Sugar kinases, ribokinase family. | Iold protein; COG3962 Acetolactate synthase; Belongs to the TPP enzyme family. | 0.983 |
| EAQ07192.1 | EAQ07194.1 | SKA53_02311 | SKA53_02321 | 5-dehydro-2-deoxygluconokinase; COG0524 Sugar kinases, ribokinase family. | MocC-like protein; COG1082 Sugar phosphate isomerases/epimerases; similar to tomyo-inositol catabolism iolE. | 0.981 |
| EAQ07192.1 | purU | SKA53_02311 | SKA53_02306 | 5-dehydro-2-deoxygluconokinase; COG0524 Sugar kinases, ribokinase family. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.774 |
| EAQ07193.1 | EAQ07192.1 | SKA53_02316 | SKA53_02311 | Iold protein; COG3962 Acetolactate synthase; Belongs to the TPP enzyme family. | 5-dehydro-2-deoxygluconokinase; COG0524 Sugar kinases, ribokinase family. | 0.983 |
| EAQ07193.1 | EAQ07194.1 | SKA53_02316 | SKA53_02321 | Iold protein; COG3962 Acetolactate synthase; Belongs to the TPP enzyme family. | MocC-like protein; COG1082 Sugar phosphate isomerases/epimerases; similar to tomyo-inositol catabolism iolE. | 0.990 |
| EAQ07193.1 | purU | SKA53_02316 | SKA53_02306 | Iold protein; COG3962 Acetolactate synthase; Belongs to the TPP enzyme family. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.773 |
| EAQ07194.1 | EAQ07192.1 | SKA53_02321 | SKA53_02311 | MocC-like protein; COG1082 Sugar phosphate isomerases/epimerases; similar to tomyo-inositol catabolism iolE. | 5-dehydro-2-deoxygluconokinase; COG0524 Sugar kinases, ribokinase family. | 0.981 |
| EAQ07194.1 | EAQ07193.1 | SKA53_02321 | SKA53_02316 | MocC-like protein; COG1082 Sugar phosphate isomerases/epimerases; similar to tomyo-inositol catabolism iolE. | Iold protein; COG3962 Acetolactate synthase; Belongs to the TPP enzyme family. | 0.990 |
| EAQ07194.1 | purU | SKA53_02321 | SKA53_02306 | MocC-like protein; COG1082 Sugar phosphate isomerases/epimerases; similar to tomyo-inositol catabolism iolE. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.773 |
| EAQ07520.1 | EAQ06946.1 | SKA53_11823 | SKA53_15401 | Phosphate acetyltransferase; COG0281 Malic enzyme. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.434 |