| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ06723.1 | EAQ07907.1 | SKA53_14286 | SKA53_09294 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.972 |
| EAQ06723.1 | EAQ08185.1 | SKA53_14286 | SKA53_10684 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | COG0167 Dihydroorotate dehydrogenase. | 0.965 |
| EAQ06723.1 | carA | SKA53_14286 | SKA53_07007 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | 0.959 |
| EAQ06723.1 | carB | SKA53_14286 | SKA53_09594 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.965 |
| EAQ06723.1 | pyrB | SKA53_14286 | SKA53_14296 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| EAQ06723.1 | pyrC | SKA53_14286 | SKA53_02606 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.846 |
| EAQ06723.1 | pyrE | SKA53_14286 | SKA53_02601 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.883 |
| EAQ07252.1 | pyrC | SKA53_02611 | SKA53_02606 | COG1960 Acyl-CoA dehydrogenases. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.615 |
| EAQ07252.1 | pyrE | SKA53_02611 | SKA53_02601 | COG1960 Acyl-CoA dehydrogenases. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.528 |
| EAQ07735.1 | EAQ07907.1 | SKA53_12898 | SKA53_09294 | HAD-superfamily subfamily IIA hydrolase; COG0647 Predicted sugar phosphatases of the HAD superfamily. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.514 |
| EAQ07735.1 | EAQ08185.1 | SKA53_12898 | SKA53_10684 | HAD-superfamily subfamily IIA hydrolase; COG0647 Predicted sugar phosphatases of the HAD superfamily. | COG0167 Dihydroorotate dehydrogenase. | 0.433 |
| EAQ07735.1 | pyrC | SKA53_12898 | SKA53_02606 | HAD-superfamily subfamily IIA hydrolase; COG0647 Predicted sugar phosphatases of the HAD superfamily. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.737 |
| EAQ07735.1 | pyrE | SKA53_12898 | SKA53_02601 | HAD-superfamily subfamily IIA hydrolase; COG0647 Predicted sugar phosphatases of the HAD superfamily. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.493 |
| EAQ07907.1 | EAQ06723.1 | SKA53_09294 | SKA53_14286 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.972 |
| EAQ07907.1 | EAQ07735.1 | SKA53_09294 | SKA53_12898 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | HAD-superfamily subfamily IIA hydrolase; COG0647 Predicted sugar phosphatases of the HAD superfamily. | 0.514 |
| EAQ07907.1 | EAQ08185.1 | SKA53_09294 | SKA53_10684 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | COG0167 Dihydroorotate dehydrogenase. | 0.828 |
| EAQ07907.1 | carA | SKA53_09294 | SKA53_07007 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | 0.924 |
| EAQ07907.1 | carB | SKA53_09294 | SKA53_09594 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.958 |
| EAQ07907.1 | pyrB | SKA53_09294 | SKA53_14296 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.930 |
| EAQ07907.1 | pyrC | SKA53_09294 | SKA53_02606 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.979 |