| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05733.1 | EAQ06822.1 | SKA53_06502 | SKA53_14781 | Hypothetical protein; COG0541 Signal recognition particle GTPase. | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.888 |
| EAQ05733.1 | coaD | SKA53_06502 | SKA53_02866 | Hypothetical protein; COG0541 Signal recognition particle GTPase. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.904 |
| EAQ05733.1 | coaE | SKA53_06502 | SKA53_11903 | Hypothetical protein; COG0541 Signal recognition particle GTPase. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.412 |
| EAQ05733.1 | coaX | SKA53_06502 | SKA53_06057 | Hypothetical protein; COG0541 Signal recognition particle GTPase. | Transcriptional activator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.492 |
| EAQ06643.1 | coaD | SKA53_13886 | SKA53_02866 | COG0742 N6-adenine-specific methylase. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.856 |
| EAQ06822.1 | EAQ05733.1 | SKA53_14781 | SKA53_06502 | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Hypothetical protein; COG0541 Signal recognition particle GTPase. | 0.888 |
| EAQ06822.1 | EAQ07733.1 | SKA53_14781 | SKA53_12888 | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Riboflavin biosynthesis protein RibF; COG0196 FAD synthase; Belongs to the ribF family. | 0.751 |
| EAQ06822.1 | coaD | SKA53_14781 | SKA53_02866 | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.930 |
| EAQ06822.1 | coaE | SKA53_14781 | SKA53_11903 | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.770 |
| EAQ06822.1 | coaX | SKA53_14781 | SKA53_06057 | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Transcriptional activator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.909 |
| EAQ06822.1 | ribB | SKA53_14781 | SKA53_01971 | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.667 |
| EAQ07302.1 | coaD | SKA53_02861 | SKA53_02866 | COG0517 FOG: CBS domain. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.699 |
| EAQ07302.1 | guaA | SKA53_02861 | SKA53_04933 | COG0517 FOG: CBS domain. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.923 |
| EAQ07733.1 | EAQ06822.1 | SKA53_12888 | SKA53_14781 | Riboflavin biosynthesis protein RibF; COG0196 FAD synthase; Belongs to the ribF family. | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.751 |
| EAQ07733.1 | coaD | SKA53_12888 | SKA53_02866 | Riboflavin biosynthesis protein RibF; COG0196 FAD synthase; Belongs to the ribF family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.735 |
| EAQ07733.1 | coaE | SKA53_12888 | SKA53_11903 | Riboflavin biosynthesis protein RibF; COG0196 FAD synthase; Belongs to the ribF family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.583 |
| EAQ07733.1 | guaA | SKA53_12888 | SKA53_04933 | Riboflavin biosynthesis protein RibF; COG0196 FAD synthase; Belongs to the ribF family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.483 |
| EAQ07733.1 | nadE | SKA53_12888 | SKA53_08994 | Riboflavin biosynthesis protein RibF; COG0196 FAD synthase; Belongs to the ribF family. | NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.607 |
| EAQ07733.1 | ribB | SKA53_12888 | SKA53_01971 | Riboflavin biosynthesis protein RibF; COG0196 FAD synthase; Belongs to the ribF family. | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.885 |
| coaD | EAQ05733.1 | SKA53_02866 | SKA53_06502 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Hypothetical protein; COG0541 Signal recognition particle GTPase. | 0.904 |