| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ07111.1 | EAQ07315.1 | SKA53_01906 | SKA53_02926 | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.938 |
| EAQ07111.1 | guaB | SKA53_01906 | SKA53_03244 | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.450 |
| EAQ07111.1 | murI | SKA53_01906 | SKA53_02936 | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.888 |
| EAQ07315.1 | EAQ07111.1 | SKA53_02926 | SKA53_01906 | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.938 |
| EAQ07315.1 | EAQ07316.1 | SKA53_02926 | SKA53_02931 | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | Acyltransferase domain protein; COG3176 putative hemolysin. | 0.561 |
| EAQ07315.1 | EAQ07320.1 | SKA53_02926 | SKA53_02951 | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | Hypothetical protein; COG3926 putative secretion activating protein. | 0.556 |
| EAQ07315.1 | argC | SKA53_02926 | SKA53_02941 | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.710 |
| EAQ07315.1 | ccmE | SKA53_02926 | SKA53_02946 | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. | 0.705 |
| EAQ07315.1 | murI | SKA53_02926 | SKA53_02936 | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.740 |
| EAQ07316.1 | EAQ07315.1 | SKA53_02931 | SKA53_02926 | Acyltransferase domain protein; COG3176 putative hemolysin. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.561 |
| EAQ07316.1 | EAQ07320.1 | SKA53_02931 | SKA53_02951 | Acyltransferase domain protein; COG3176 putative hemolysin. | Hypothetical protein; COG3926 putative secretion activating protein. | 0.611 |
| EAQ07316.1 | argC | SKA53_02931 | SKA53_02941 | Acyltransferase domain protein; COG3176 putative hemolysin. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.769 |
| EAQ07316.1 | ccmE | SKA53_02931 | SKA53_02946 | Acyltransferase domain protein; COG3176 putative hemolysin. | Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. | 0.783 |
| EAQ07316.1 | murI | SKA53_02931 | SKA53_02936 | Acyltransferase domain protein; COG3176 putative hemolysin. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.817 |
| EAQ07320.1 | EAQ07315.1 | SKA53_02951 | SKA53_02926 | Hypothetical protein; COG3926 putative secretion activating protein. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.556 |
| EAQ07320.1 | EAQ07316.1 | SKA53_02951 | SKA53_02931 | Hypothetical protein; COG3926 putative secretion activating protein. | Acyltransferase domain protein; COG3176 putative hemolysin. | 0.611 |
| EAQ07320.1 | argC | SKA53_02951 | SKA53_02941 | Hypothetical protein; COG3926 putative secretion activating protein. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.761 |
| EAQ07320.1 | ccmE | SKA53_02951 | SKA53_02946 | Hypothetical protein; COG3926 putative secretion activating protein. | Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. | 0.762 |
| EAQ07320.1 | murI | SKA53_02951 | SKA53_02936 | Hypothetical protein; COG3926 putative secretion activating protein. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.733 |
| EAQ07525.1 | guaA | SKA53_11848 | SKA53_04933 | Putative deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.963 |