| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05278.1 | EAQ05281.1 | SKA53_05865 | SKA53_05880 | Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily; COG0526 Thiol-disulfide isomerase and thioredoxins. | ABC heme exporter, inner membrane subunit CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | 0.937 |
| EAQ05278.1 | EAQ07323.1 | SKA53_05865 | SKA53_02966 | Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily; COG0526 Thiol-disulfide isomerase and thioredoxins. | Cytochrome c-type biogenesis protein CcmF; COG1138 Cytochrome c biogenesis factor. | 0.985 |
| EAQ05278.1 | EAQ07324.1 | SKA53_05865 | SKA53_02971 | Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily; COG0526 Thiol-disulfide isomerase and thioredoxins. | Cytochrome c biogenesis family protein; Possible subunit of a heme lyase. | 0.935 |
| EAQ05278.1 | ccmA | SKA53_05865 | SKA53_05885 | Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily; COG0526 Thiol-disulfide isomerase and thioredoxins. | ABC heme exporter, ATPase subunt CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | 0.818 |
| EAQ05278.1 | ccmC | SKA53_05865 | SKA53_05875 | Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily; COG0526 Thiol-disulfide isomerase and thioredoxins. | ABC heme exporter, inner membrane subunit CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. | 0.970 |
| EAQ05278.1 | ccmE | SKA53_05865 | SKA53_02946 | Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily; COG0526 Thiol-disulfide isomerase and thioredoxins. | Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. | 0.925 |
| EAQ05281.1 | EAQ05278.1 | SKA53_05880 | SKA53_05865 | ABC heme exporter, inner membrane subunit CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily; COG0526 Thiol-disulfide isomerase and thioredoxins. | 0.937 |
| EAQ05281.1 | EAQ07323.1 | SKA53_05880 | SKA53_02966 | ABC heme exporter, inner membrane subunit CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Cytochrome c-type biogenesis protein CcmF; COG1138 Cytochrome c biogenesis factor. | 0.891 |
| EAQ05281.1 | EAQ07324.1 | SKA53_05880 | SKA53_02971 | ABC heme exporter, inner membrane subunit CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Cytochrome c biogenesis family protein; Possible subunit of a heme lyase. | 0.850 |
| EAQ05281.1 | ccmA | SKA53_05880 | SKA53_05885 | ABC heme exporter, inner membrane subunit CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | ABC heme exporter, ATPase subunt CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | 0.999 |
| EAQ05281.1 | ccmC | SKA53_05880 | SKA53_05875 | ABC heme exporter, inner membrane subunit CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | ABC heme exporter, inner membrane subunit CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. | 0.999 |
| EAQ05281.1 | ccmE | SKA53_05880 | SKA53_02946 | ABC heme exporter, inner membrane subunit CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. | 0.986 |
| EAQ07316.1 | EAQ07320.1 | SKA53_02931 | SKA53_02951 | Acyltransferase domain protein; COG3176 putative hemolysin. | Hypothetical protein; COG3926 putative secretion activating protein. | 0.610 |
| EAQ07316.1 | EAQ07323.1 | SKA53_02931 | SKA53_02966 | Acyltransferase domain protein; COG3176 putative hemolysin. | Cytochrome c-type biogenesis protein CcmF; COG1138 Cytochrome c biogenesis factor. | 0.441 |
| EAQ07316.1 | EAQ07324.1 | SKA53_02931 | SKA53_02971 | Acyltransferase domain protein; COG3176 putative hemolysin. | Cytochrome c biogenesis family protein; Possible subunit of a heme lyase. | 0.441 |
| EAQ07316.1 | argC | SKA53_02931 | SKA53_02941 | Acyltransferase domain protein; COG3176 putative hemolysin. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.763 |
| EAQ07316.1 | ccmE | SKA53_02931 | SKA53_02946 | Acyltransferase domain protein; COG3176 putative hemolysin. | Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. | 0.768 |
| EAQ07316.1 | murI | SKA53_02931 | SKA53_02936 | Acyltransferase domain protein; COG3176 putative hemolysin. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.811 |
| EAQ07320.1 | EAQ07316.1 | SKA53_02951 | SKA53_02931 | Hypothetical protein; COG3926 putative secretion activating protein. | Acyltransferase domain protein; COG3176 putative hemolysin. | 0.610 |
| EAQ07320.1 | EAQ07323.1 | SKA53_02951 | SKA53_02966 | Hypothetical protein; COG3926 putative secretion activating protein. | Cytochrome c-type biogenesis protein CcmF; COG1138 Cytochrome c biogenesis factor. | 0.707 |