| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05231.1 | EAQ06946.1 | SKA53_05630 | SKA53_15401 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.511 |
| EAQ05231.1 | EAQ07359.1 | SKA53_05630 | SKA53_03146 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | 0.417 |
| EAQ05231.1 | EAQ08212.1 | SKA53_05630 | SKA53_10819 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 0.889 |
| EAQ06946.1 | EAQ05231.1 | SKA53_15401 | SKA53_05630 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.511 |
| EAQ06946.1 | EAQ07359.1 | SKA53_15401 | SKA53_03146 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | 0.692 |
| EAQ06946.1 | EAQ07361.1 | SKA53_15401 | SKA53_03156 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | CobA, uroporphyrin-III C-methyltransferase; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | 0.499 |
| EAQ06946.1 | EAQ07363.1 | SKA53_15401 | SKA53_03166 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | COG2099 Precorrin-6x reductase. | 0.414 |
| EAQ06946.1 | EAQ08212.1 | SKA53_15401 | SKA53_10819 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 0.448 |
| EAQ06946.1 | cobB | SKA53_15401 | SKA53_03151 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.405 |
| EAQ07359.1 | EAQ05231.1 | SKA53_03146 | SKA53_05630 | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.417 |
| EAQ07359.1 | EAQ06946.1 | SKA53_03146 | SKA53_15401 | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.692 |
| EAQ07359.1 | EAQ07361.1 | SKA53_03146 | SKA53_03156 | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | CobA, uroporphyrin-III C-methyltransferase; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | 0.740 |
| EAQ07359.1 | EAQ07363.1 | SKA53_03146 | SKA53_03166 | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | COG2099 Precorrin-6x reductase. | 0.609 |
| EAQ07359.1 | EAQ07364.1 | SKA53_03146 | SKA53_03171 | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | DNA-3-methyladenine glycosylase II, putative; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase. | 0.782 |
| EAQ07359.1 | EAQ07365.1 | SKA53_03146 | SKA53_03176 | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | Phospholipase/carboxylesterase family protein; COG0400 Predicted esterase. | 0.782 |
| EAQ07359.1 | EAQ08057.1 | SKA53_03146 | SKA53_10044 | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | COG5469 Predicted metal-binding protein. | 0.481 |
| EAQ07359.1 | EAQ08212.1 | SKA53_03146 | SKA53_10819 | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 0.414 |
| EAQ07359.1 | cbiD | SKA53_03146 | SKA53_03161 | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.555 |
| EAQ07359.1 | cobB | SKA53_03146 | SKA53_03151 | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.850 |
| EAQ07361.1 | EAQ06946.1 | SKA53_03156 | SKA53_15401 | CobA, uroporphyrin-III C-methyltransferase; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.499 |