| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ06946.1 | EAQ07363.1 | SKA53_15401 | SKA53_03166 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | COG2099 Precorrin-6x reductase. | 0.406 |
| EAQ06946.1 | EAQ07366.1 | SKA53_15401 | SKA53_03181 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | HNH endonuclease family protein; COG1403 Restriction endonuclease. | 0.780 |
| EAQ06946.1 | folD | SKA53_15401 | SKA53_08536 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | folD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.733 |
| EAQ07363.1 | EAQ06946.1 | SKA53_03166 | SKA53_15401 | COG2099 Precorrin-6x reductase. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.406 |
| EAQ07363.1 | EAQ07364.1 | SKA53_03166 | SKA53_03171 | COG2099 Precorrin-6x reductase. | DNA-3-methyladenine glycosylase II, putative; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase. | 0.855 |
| EAQ07363.1 | EAQ07365.1 | SKA53_03166 | SKA53_03176 | COG2099 Precorrin-6x reductase. | Phospholipase/carboxylesterase family protein; COG0400 Predicted esterase. | 0.855 |
| EAQ07363.1 | EAQ07366.1 | SKA53_03166 | SKA53_03181 | COG2099 Precorrin-6x reductase. | HNH endonuclease family protein; COG1403 Restriction endonuclease. | 0.585 |
| EAQ07363.1 | cbiD | SKA53_03166 | SKA53_03161 | COG2099 Precorrin-6x reductase. | cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.998 |
| EAQ07364.1 | EAQ07363.1 | SKA53_03171 | SKA53_03166 | DNA-3-methyladenine glycosylase II, putative; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase. | COG2099 Precorrin-6x reductase. | 0.855 |
| EAQ07364.1 | EAQ07365.1 | SKA53_03171 | SKA53_03176 | DNA-3-methyladenine glycosylase II, putative; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase. | Phospholipase/carboxylesterase family protein; COG0400 Predicted esterase. | 0.913 |
| EAQ07364.1 | EAQ07366.1 | SKA53_03171 | SKA53_03181 | DNA-3-methyladenine glycosylase II, putative; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase. | HNH endonuclease family protein; COG1403 Restriction endonuclease. | 0.654 |
| EAQ07364.1 | cbiD | SKA53_03171 | SKA53_03161 | DNA-3-methyladenine glycosylase II, putative; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase. | cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.855 |
| EAQ07365.1 | EAQ07363.1 | SKA53_03176 | SKA53_03166 | Phospholipase/carboxylesterase family protein; COG0400 Predicted esterase. | COG2099 Precorrin-6x reductase. | 0.855 |
| EAQ07365.1 | EAQ07364.1 | SKA53_03176 | SKA53_03171 | Phospholipase/carboxylesterase family protein; COG0400 Predicted esterase. | DNA-3-methyladenine glycosylase II, putative; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase. | 0.913 |
| EAQ07365.1 | EAQ07366.1 | SKA53_03176 | SKA53_03181 | Phospholipase/carboxylesterase family protein; COG0400 Predicted esterase. | HNH endonuclease family protein; COG1403 Restriction endonuclease. | 0.641 |
| EAQ07365.1 | cbiD | SKA53_03176 | SKA53_03161 | Phospholipase/carboxylesterase family protein; COG0400 Predicted esterase. | cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.855 |
| EAQ07366.1 | EAQ06946.1 | SKA53_03181 | SKA53_15401 | HNH endonuclease family protein; COG1403 Restriction endonuclease. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.780 |
| EAQ07366.1 | EAQ07363.1 | SKA53_03181 | SKA53_03166 | HNH endonuclease family protein; COG1403 Restriction endonuclease. | COG2099 Precorrin-6x reductase. | 0.585 |
| EAQ07366.1 | EAQ07364.1 | SKA53_03181 | SKA53_03171 | HNH endonuclease family protein; COG1403 Restriction endonuclease. | DNA-3-methyladenine glycosylase II, putative; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase. | 0.654 |
| EAQ07366.1 | EAQ07365.1 | SKA53_03181 | SKA53_03176 | HNH endonuclease family protein; COG1403 Restriction endonuclease. | Phospholipase/carboxylesterase family protein; COG0400 Predicted esterase. | 0.641 |