| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05211.1 | EAQ05212.1 | SKA53_03309 | SKA53_03314 | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | 0.992 |
| EAQ05211.1 | EAQ05426.1 | SKA53_03309 | SKA53_03419 | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | Putative dimethylamine corrinoid protein; COG5012 Predicted cobalamin binding protein. | 0.996 |
| EAQ05211.1 | EAQ05427.1 | SKA53_03309 | SKA53_03424 | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | 0.998 |
| EAQ05211.1 | EAQ05916.1 | SKA53_03309 | SKA53_07421 | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | COG2873 O-acetylhomoserine sulfhydrylase. | 0.880 |
| EAQ05211.1 | EAQ06931.1 | SKA53_03309 | SKA53_15326 | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.964 |
| EAQ05211.1 | EAQ06946.1 | SKA53_03309 | SKA53_15401 | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.922 |
| EAQ05211.1 | EAQ08046.1 | SKA53_03309 | SKA53_09989 | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | Aminotransferase, classes I and II; COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities. | 0.851 |
| EAQ05211.1 | ahcY | SKA53_03309 | SKA53_11523 | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.886 |
| EAQ05211.1 | fhs | SKA53_03309 | SKA53_08541 | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | Formate--tetrahydrofolate ligase; COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | 0.880 |
| EAQ05211.1 | metK | SKA53_03309 | SKA53_01171 | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.885 |
| EAQ05212.1 | EAQ05211.1 | SKA53_03314 | SKA53_03309 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | 0.992 |
| EAQ05212.1 | EAQ05426.1 | SKA53_03314 | SKA53_03419 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | Putative dimethylamine corrinoid protein; COG5012 Predicted cobalamin binding protein. | 0.844 |
| EAQ05212.1 | EAQ05427.1 | SKA53_03314 | SKA53_03424 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | 0.947 |
| EAQ05212.1 | EAQ05916.1 | SKA53_03314 | SKA53_07421 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | COG2873 O-acetylhomoserine sulfhydrylase. | 0.432 |
| EAQ05212.1 | EAQ06931.1 | SKA53_03314 | SKA53_15326 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.907 |
| EAQ05212.1 | EAQ06946.1 | SKA53_03314 | SKA53_15401 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.995 |
| EAQ05212.1 | ahcY | SKA53_03314 | SKA53_11523 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.524 |
| EAQ05212.1 | fhs | SKA53_03314 | SKA53_08541 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | Formate--tetrahydrofolate ligase; COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | 0.493 |
| EAQ05212.1 | metK | SKA53_03314 | SKA53_01171 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.772 |
| EAQ05426.1 | EAQ05211.1 | SKA53_03419 | SKA53_03309 | Putative dimethylamine corrinoid protein; COG5012 Predicted cobalamin binding protein. | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | 0.996 |