| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05474.1 | EAQ05479.1 | SKA53_03659 | SKA53_03684 | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 0.959 |
| EAQ05474.1 | EAQ05480.1 | SKA53_03659 | SKA53_03689 | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 0.961 |
| EAQ05474.1 | EAQ05481.1 | SKA53_03659 | SKA53_03694 | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | 4-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit. | 0.952 |
| EAQ05474.1 | EAQ05583.1 | SKA53_03659 | SKA53_00814 | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 0.954 |
| EAQ05474.1 | EAQ05584.1 | SKA53_03659 | SKA53_00819 | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 0.959 |
| EAQ05474.1 | EAQ05585.1 | SKA53_03659 | SKA53_00824 | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | 4-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit. | 0.952 |
| EAQ05474.1 | purA | SKA53_03659 | SKA53_07496 | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.912 |
| EAQ05474.1 | purC | SKA53_03659 | SKA53_03434 | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | 0.912 |
| EAQ05474.1 | purD | SKA53_03659 | SKA53_02076 | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.896 |
| EAQ05474.1 | purH | SKA53_03659 | SKA53_12688 | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.897 |
| EAQ05479.1 | EAQ05474.1 | SKA53_03684 | SKA53_03659 | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | 0.959 |
| EAQ05479.1 | EAQ05480.1 | SKA53_03684 | SKA53_03689 | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 0.997 |
| EAQ05479.1 | EAQ05481.1 | SKA53_03684 | SKA53_03694 | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 4-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit. | 0.971 |
| EAQ05479.1 | EAQ05584.1 | SKA53_03684 | SKA53_00819 | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 0.987 |
| EAQ05479.1 | EAQ05585.1 | SKA53_03684 | SKA53_00824 | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 4-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit. | 0.877 |
| EAQ05480.1 | EAQ05474.1 | SKA53_03689 | SKA53_03659 | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | 0.961 |
| EAQ05480.1 | EAQ05479.1 | SKA53_03689 | SKA53_03684 | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 0.997 |
| EAQ05480.1 | EAQ05481.1 | SKA53_03689 | SKA53_03694 | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 4-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit. | 0.972 |
| EAQ05480.1 | EAQ05583.1 | SKA53_03689 | SKA53_00814 | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 0.987 |
| EAQ05480.1 | EAQ05585.1 | SKA53_03689 | SKA53_00824 | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 4-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit. | 0.882 |