| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ06243.1 | EAQ06244.1 | SKA53_04128 | SKA53_04133 | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | Isocitrate lyase family protein; COG2513 PEP phosphonomutase and related enzymes. | 0.958 |
| EAQ06243.1 | EAQ06245.1 | SKA53_04128 | SKA53_04138 | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | Isochorismatase family protein; COG1335 Amidases related to nicotinamidase. | 0.955 |
| EAQ06243.1 | EAQ06781.1 | SKA53_04128 | SKA53_14576 | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. | 0.998 |
| EAQ06243.1 | EAQ06782.1 | SKA53_04128 | SKA53_14581 | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | COG2142 Succinate dehydrogenase, hydrophobic anchor subunit. | 0.980 |
| EAQ06243.1 | EAQ06786.1 | SKA53_04128 | SKA53_14601 | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.998 |
| EAQ06243.1 | EAQ07148.1 | SKA53_04128 | SKA53_02091 | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | 0.976 |
| EAQ06243.1 | EAQ07315.1 | SKA53_04128 | SKA53_02926 | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.986 |
| EAQ06243.1 | EAQ07878.1 | SKA53_04128 | SKA53_09149 | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | COG1145 Ferredoxin. | 0.953 |
| EAQ06243.1 | sucC | SKA53_04128 | SKA53_14531 | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.958 |
| EAQ06243.1 | sucD | SKA53_04128 | SKA53_14526 | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | Succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.956 |
| EAQ06244.1 | EAQ06243.1 | SKA53_04133 | SKA53_04128 | Isocitrate lyase family protein; COG2513 PEP phosphonomutase and related enzymes. | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | 0.958 |
| EAQ06244.1 | EAQ06245.1 | SKA53_04133 | SKA53_04138 | Isocitrate lyase family protein; COG2513 PEP phosphonomutase and related enzymes. | Isochorismatase family protein; COG1335 Amidases related to nicotinamidase. | 0.945 |
| EAQ06244.1 | EAQ06781.1 | SKA53_04133 | SKA53_14576 | Isocitrate lyase family protein; COG2513 PEP phosphonomutase and related enzymes. | COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. | 0.540 |
| EAQ06244.1 | EAQ06782.1 | SKA53_04133 | SKA53_14581 | Isocitrate lyase family protein; COG2513 PEP phosphonomutase and related enzymes. | COG2142 Succinate dehydrogenase, hydrophobic anchor subunit. | 0.516 |
| EAQ06244.1 | EAQ06786.1 | SKA53_04133 | SKA53_14601 | Isocitrate lyase family protein; COG2513 PEP phosphonomutase and related enzymes. | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.581 |
| EAQ06244.1 | EAQ07315.1 | SKA53_04133 | SKA53_02926 | Isocitrate lyase family protein; COG2513 PEP phosphonomutase and related enzymes. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.465 |
| EAQ06244.1 | sucC | SKA53_04133 | SKA53_14531 | Isocitrate lyase family protein; COG2513 PEP phosphonomutase and related enzymes. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.879 |
| EAQ06244.1 | sucD | SKA53_04133 | SKA53_14526 | Isocitrate lyase family protein; COG2513 PEP phosphonomutase and related enzymes. | Succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.891 |
| EAQ06245.1 | EAQ06243.1 | SKA53_04138 | SKA53_04128 | Isochorismatase family protein; COG1335 Amidases related to nicotinamidase. | 3-ketosteroid dehydrogenase, putative; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | 0.955 |
| EAQ06245.1 | EAQ06244.1 | SKA53_04138 | SKA53_04133 | Isochorismatase family protein; COG1335 Amidases related to nicotinamidase. | Isocitrate lyase family protein; COG2513 PEP phosphonomutase and related enzymes. | 0.945 |