| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05900.1 | EAQ06328.1 | SKA53_07341 | SKA53_04553 | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | Heme peroxidase; COG1200 RecG-like helicase. | 0.660 |
| EAQ05900.1 | EAQ07102.1 | SKA53_07341 | SKA53_01861 | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | COG0608 Single-stranded DNA-specific exonuclease. | 0.580 |
| EAQ05900.1 | EAQ07676.1 | SKA53_07341 | SKA53_12603 | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | COG0514 Superfamily II DNA helicase. | 0.984 |
| EAQ05900.1 | ligA | SKA53_07341 | SKA53_04548 | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.920 |
| EAQ05900.1 | polA | SKA53_07341 | SKA53_15116 | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.821 |
| EAQ05900.1 | recA | SKA53_07341 | SKA53_03339 | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.973 |
| EAQ05900.1 | recF | SKA53_07341 | SKA53_10539 | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | Recombination protein F; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.582 |
| EAQ05900.1 | ruvA | SKA53_07341 | SKA53_08606 | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | Holliday junction DNA helicase motor protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.458 |
| EAQ05900.1 | topA | SKA53_07341 | SKA53_08441 | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.847 |
| EAQ06326.1 | EAQ06328.1 | SKA53_04543 | SKA53_04553 | COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. | Heme peroxidase; COG1200 RecG-like helicase. | 0.692 |
| EAQ06326.1 | ligA | SKA53_04543 | SKA53_04548 | COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.587 |
| EAQ06326.1 | recF | SKA53_04543 | SKA53_10539 | COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. | Recombination protein F; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.495 |
| EAQ06328.1 | EAQ05900.1 | SKA53_04553 | SKA53_07341 | Heme peroxidase; COG1200 RecG-like helicase. | Putative uvrD/DNA Helicase II; COG0210 Superfamily I DNA and RNA helicases. | 0.660 |
| EAQ06328.1 | EAQ06326.1 | SKA53_04553 | SKA53_04543 | Heme peroxidase; COG1200 RecG-like helicase. | COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. | 0.692 |
| EAQ06328.1 | EAQ07102.1 | SKA53_04553 | SKA53_01861 | Heme peroxidase; COG1200 RecG-like helicase. | COG0608 Single-stranded DNA-specific exonuclease. | 0.647 |
| EAQ06328.1 | EAQ07676.1 | SKA53_04553 | SKA53_12603 | Heme peroxidase; COG1200 RecG-like helicase. | COG0514 Superfamily II DNA helicase. | 0.634 |
| EAQ06328.1 | ligA | SKA53_04553 | SKA53_04548 | Heme peroxidase; COG1200 RecG-like helicase. | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.928 |
| EAQ06328.1 | polA | SKA53_04553 | SKA53_15116 | Heme peroxidase; COG1200 RecG-like helicase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.698 |
| EAQ06328.1 | recA | SKA53_04553 | SKA53_03339 | Heme peroxidase; COG1200 RecG-like helicase. | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.609 |
| EAQ06328.1 | recF | SKA53_04553 | SKA53_10539 | Heme peroxidase; COG1200 RecG-like helicase. | Recombination protein F; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.653 |