| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ06335.1 | EAQ06336.1 | SKA53_04588 | SKA53_04593 | COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | 0.993 |
| EAQ06335.1 | EAQ06337.1 | SKA53_04588 | SKA53_04598 | COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | Transcriptional regulator, AsnC family; COG1522 Transcriptional regulators. | 0.885 |
| EAQ06335.1 | EAQ06339.1 | SKA53_04588 | SKA53_04608 | COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | Hypothetical protein. | 0.550 |
| EAQ06335.1 | gyrA | SKA53_04588 | SKA53_04583 | COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.529 |
| EAQ06336.1 | EAQ06335.1 | SKA53_04593 | SKA53_04588 | COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | 0.993 |
| EAQ06336.1 | EAQ06337.1 | SKA53_04593 | SKA53_04598 | COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | Transcriptional regulator, AsnC family; COG1522 Transcriptional regulators. | 0.857 |
| EAQ06336.1 | EAQ06339.1 | SKA53_04593 | SKA53_04608 | COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | Hypothetical protein. | 0.550 |
| EAQ06336.1 | EAQ08212.1 | SKA53_04593 | SKA53_10819 | COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 0.868 |
| EAQ06336.1 | gyrA | SKA53_04593 | SKA53_04583 | COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.552 |
| EAQ06337.1 | EAQ06335.1 | SKA53_04598 | SKA53_04588 | Transcriptional regulator, AsnC family; COG1522 Transcriptional regulators. | COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | 0.885 |
| EAQ06337.1 | EAQ06336.1 | SKA53_04598 | SKA53_04593 | Transcriptional regulator, AsnC family; COG1522 Transcriptional regulators. | COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | 0.857 |
| EAQ06337.1 | EAQ06339.1 | SKA53_04598 | SKA53_04608 | Transcriptional regulator, AsnC family; COG1522 Transcriptional regulators. | Hypothetical protein. | 0.773 |
| EAQ06337.1 | EAQ07266.1 | SKA53_04598 | SKA53_02681 | Transcriptional regulator, AsnC family; COG1522 Transcriptional regulators. | Siroheme synthetase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.658 |
| EAQ06337.1 | EAQ07315.1 | SKA53_04598 | SKA53_02926 | Transcriptional regulator, AsnC family; COG1522 Transcriptional regulators. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.431 |
| EAQ06337.1 | EAQ08212.1 | SKA53_04598 | SKA53_10819 | Transcriptional regulator, AsnC family; COG1522 Transcriptional regulators. | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 0.519 |
| EAQ06337.1 | gyrA | SKA53_04598 | SKA53_04583 | Transcriptional regulator, AsnC family; COG1522 Transcriptional regulators. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.402 |
| EAQ06339.1 | EAQ06335.1 | SKA53_04608 | SKA53_04588 | Hypothetical protein. | COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | 0.550 |
| EAQ06339.1 | EAQ06336.1 | SKA53_04608 | SKA53_04593 | Hypothetical protein. | COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | 0.550 |
| EAQ06339.1 | EAQ06337.1 | SKA53_04608 | SKA53_04598 | Hypothetical protein. | Transcriptional regulator, AsnC family; COG1522 Transcriptional regulators. | 0.773 |
| EAQ07266.1 | EAQ06337.1 | SKA53_02681 | SKA53_04598 | Siroheme synthetase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Transcriptional regulator, AsnC family; COG1522 Transcriptional regulators. | 0.658 |