| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ06090.1 | EAQ06396.1 | SKA53_08291 | SKA53_04893 | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | Competence/damage-inducible protein CinA domain protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | 0.820 |
| EAQ06090.1 | EAQ06479.1 | SKA53_08291 | SKA53_05308 | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | mazG family protein; COG1694 Predicted pyrophosphatase. | 0.831 |
| EAQ06090.1 | EAQ06626.1 | SKA53_08291 | SKA53_13801 | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | Molybdenum cofactor biosynthesis domain protein; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA. | 0.487 |
| EAQ06090.1 | EAQ07905.1 | SKA53_08291 | SKA53_09284 | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.822 |
| EAQ06090.1 | nadD | SKA53_08291 | SKA53_14836 | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | Nicotinic acid mononucleotide adenyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.823 |
| EAQ06090.1 | nadE | SKA53_08291 | SKA53_08994 | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.828 |
| EAQ06090.1 | pncB | SKA53_08291 | SKA53_10494 | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.834 |
| EAQ06090.1 | surE | SKA53_08291 | SKA53_02561 | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.832 |
| EAQ06395.1 | EAQ06396.1 | SKA53_04888 | SKA53_04893 | Phosphatidylglycerophosphatase, putative; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). | Competence/damage-inducible protein CinA domain protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | 0.853 |
| EAQ06395.1 | ispDF | SKA53_04888 | SKA53_04883 | Phosphatidylglycerophosphatase, putative; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.884 |
| EAQ06396.1 | EAQ06090.1 | SKA53_04893 | SKA53_08291 | Competence/damage-inducible protein CinA domain protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | 0.820 |
| EAQ06396.1 | EAQ06395.1 | SKA53_04893 | SKA53_04888 | Competence/damage-inducible protein CinA domain protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | Phosphatidylglycerophosphatase, putative; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). | 0.853 |
| EAQ06396.1 | EAQ06479.1 | SKA53_04893 | SKA53_05308 | Competence/damage-inducible protein CinA domain protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | mazG family protein; COG1694 Predicted pyrophosphatase. | 0.815 |
| EAQ06396.1 | EAQ06626.1 | SKA53_04893 | SKA53_13801 | Competence/damage-inducible protein CinA domain protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | Molybdenum cofactor biosynthesis domain protein; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA. | 0.851 |
| EAQ06396.1 | EAQ07905.1 | SKA53_04893 | SKA53_09284 | Competence/damage-inducible protein CinA domain protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.824 |
| EAQ06396.1 | ispDF | SKA53_04893 | SKA53_04883 | Competence/damage-inducible protein CinA domain protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.853 |
| EAQ06396.1 | nadD | SKA53_04893 | SKA53_14836 | Competence/damage-inducible protein CinA domain protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | Nicotinic acid mononucleotide adenyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.907 |
| EAQ06396.1 | nadE | SKA53_04893 | SKA53_08994 | Competence/damage-inducible protein CinA domain protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.909 |
| EAQ06396.1 | pncB | SKA53_04893 | SKA53_10494 | Competence/damage-inducible protein CinA domain protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.899 |
| EAQ06396.1 | surE | SKA53_04893 | SKA53_02561 | Competence/damage-inducible protein CinA domain protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.826 |