guaA protein (Yoonia vestfoldensis SKA53) - STRING interaction network

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Score

guaA

GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (519 aa)

Predicted Functional Partners:

guaB

0.999

apt

0.973

argS

0.971

gmk

0.966

pyrG

0.965

hisA

0.953

EAQ05341.1

0.951

EAQ06949.1

0.951

purH

0.950

rplK

0.949

Your Current Organism:

Yoonia vestfoldensis SKA53

NCBI taxonomy Id: 314232
Other names: Loktanella vestfoldensis SKA53, Y. vestfoldensis SKA53

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EAQ05341.1	apt	SKA53_00155	SKA53_08371	Putative transport integral membrane protein; COG0038 Chloride channel protein EriC.	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.531
EAQ05341.1	gmk	SKA53_00155	SKA53_04778	Putative transport integral membrane protein; COG0038 Chloride channel protein EriC.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.469
EAQ05341.1	guaA	SKA53_00155	SKA53_04933	Putative transport integral membrane protein; COG0038 Chloride channel protein EriC.	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.951
EAQ05341.1	guaB	SKA53_00155	SKA53_03244	Putative transport integral membrane protein; COG0038 Chloride channel protein EriC.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.864
EAQ05341.1	purH	SKA53_00155	SKA53_12688	Putative transport integral membrane protein; COG0038 Chloride channel protein EriC.	Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).	0.766
EAQ06949.1	apt	SKA53_01096	SKA53_08371	Arabinose 5-phosphate isomerase; COG0517 FOG: CBS domain.	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.616
EAQ06949.1	gmk	SKA53_01096	SKA53_04778	Arabinose 5-phosphate isomerase; COG0517 FOG: CBS domain.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.472
EAQ06949.1	guaA	SKA53_01096	SKA53_04933	Arabinose 5-phosphate isomerase; COG0517 FOG: CBS domain.	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.951
EAQ06949.1	guaB	SKA53_01096	SKA53_03244	Arabinose 5-phosphate isomerase; COG0517 FOG: CBS domain.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.928
EAQ06949.1	purH	SKA53_01096	SKA53_12688	Arabinose 5-phosphate isomerase; COG0517 FOG: CBS domain.	Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).	0.621
EAQ06949.1	pyrG	SKA53_01096	SKA53_07506	Arabinose 5-phosphate isomerase; COG0517 FOG: CBS domain.	CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	0.626
apt	EAQ05341.1	SKA53_08371	SKA53_00155	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Putative transport integral membrane protein; COG0038 Chloride channel protein EriC.	0.531
apt	EAQ06949.1	SKA53_08371	SKA53_01096	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Arabinose 5-phosphate isomerase; COG0517 FOG: CBS domain.	0.616
apt	gmk	SKA53_08371	SKA53_04778	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.827
apt	guaA	SKA53_08371	SKA53_04933	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.973
apt	guaB	SKA53_08371	SKA53_03244	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.924
apt	purH	SKA53_08371	SKA53_12688	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).	0.949
apt	pyrG	SKA53_08371	SKA53_07506	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	0.580
argS	gmk	SKA53_05413	SKA53_04778	COG0018 Arginyl-tRNA synthetase.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.556
argS	guaA	SKA53_05413	SKA53_04933	COG0018 Arginyl-tRNA synthetase.	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.971