| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ06949.1 | EAQ08212.1 | SKA53_01096 | SKA53_10819 | Arabinose 5-phosphate isomerase; COG0517 FOG: CBS domain. | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 0.844 |
| EAQ06949.1 | apt | SKA53_01096 | SKA53_08371 | Arabinose 5-phosphate isomerase; COG0517 FOG: CBS domain. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.559 |
| EAQ06949.1 | guaA | SKA53_01096 | SKA53_04933 | Arabinose 5-phosphate isomerase; COG0517 FOG: CBS domain. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.966 |
| EAQ06949.1 | guaB | SKA53_01096 | SKA53_03244 | Arabinose 5-phosphate isomerase; COG0517 FOG: CBS domain. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.944 |
| EAQ08212.1 | EAQ06949.1 | SKA53_10819 | SKA53_01096 | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | Arabinose 5-phosphate isomerase; COG0517 FOG: CBS domain. | 0.844 |
| EAQ08212.1 | apt | SKA53_10819 | SKA53_08371 | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.461 |
| EAQ08212.1 | argS | SKA53_10819 | SKA53_05413 | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | COG0018 Arginyl-tRNA synthetase. | 0.477 |
| EAQ08212.1 | gmk | SKA53_10819 | SKA53_04778 | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.524 |
| EAQ08212.1 | guaA | SKA53_10819 | SKA53_04933 | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.964 |
| EAQ08212.1 | guaB | SKA53_10819 | SKA53_03244 | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.966 |
| EAQ08212.1 | hisA | SKA53_10819 | SKA53_07381 | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. | 0.582 |
| EAQ08212.1 | pheT-2 | SKA53_10819 | SKA53_10114 | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | phenylalanyl-tRNA synthetase, beta subunit; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.764 |
| EAQ08212.1 | pyrG | SKA53_10819 | SKA53_07506 | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.745 |
| apt | EAQ06949.1 | SKA53_08371 | SKA53_01096 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Arabinose 5-phosphate isomerase; COG0517 FOG: CBS domain. | 0.559 |
| apt | EAQ08212.1 | SKA53_08371 | SKA53_10819 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 0.461 |
| apt | gmk | SKA53_08371 | SKA53_04778 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.955 |
| apt | guaA | SKA53_08371 | SKA53_04933 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.994 |
| apt | guaB | SKA53_08371 | SKA53_03244 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.908 |
| apt | pyrG | SKA53_08371 | SKA53_07506 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.639 |
| argS | EAQ08212.1 | SKA53_05413 | SKA53_10819 | COG0018 Arginyl-tRNA synthetase. | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 0.477 |