| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ06061.1 | EAQ06399.1 | SKA53_08146 | SKA53_04908 | Hypothetical protein; COG0642 Signal transduction histidine kinase. | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.573 |
| EAQ06061.1 | EAQ06479.1 | SKA53_08146 | SKA53_05308 | Hypothetical protein; COG0642 Signal transduction histidine kinase. | mazG family protein; COG1694 Predicted pyrophosphatase. | 0.883 |
| EAQ06061.1 | EAQ07771.1 | SKA53_08146 | SKA53_13078 | Hypothetical protein; COG0642 Signal transduction histidine kinase. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.928 |
| EAQ06061.1 | ribB | SKA53_08146 | SKA53_01971 | Hypothetical protein; COG0642 Signal transduction histidine kinase. | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.876 |
| EAQ06399.1 | EAQ06061.1 | SKA53_04908 | SKA53_08146 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Hypothetical protein; COG0642 Signal transduction histidine kinase. | 0.573 |
| EAQ06399.1 | EAQ06479.1 | SKA53_04908 | SKA53_05308 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | mazG family protein; COG1694 Predicted pyrophosphatase. | 0.845 |
| EAQ06479.1 | EAQ06061.1 | SKA53_05308 | SKA53_08146 | mazG family protein; COG1694 Predicted pyrophosphatase. | Hypothetical protein; COG0642 Signal transduction histidine kinase. | 0.883 |
| EAQ06479.1 | EAQ06399.1 | SKA53_05308 | SKA53_04908 | mazG family protein; COG1694 Predicted pyrophosphatase. | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.845 |
| EAQ06479.1 | EAQ07534.1 | SKA53_05308 | SKA53_11893 | mazG family protein; COG1694 Predicted pyrophosphatase. | Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.847 |
| EAQ06479.1 | EAQ07771.1 | SKA53_05308 | SKA53_13078 | mazG family protein; COG1694 Predicted pyrophosphatase. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.876 |
| EAQ06479.1 | coaE | SKA53_05308 | SKA53_11903 | mazG family protein; COG1694 Predicted pyrophosphatase. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.833 |
| EAQ06479.1 | pncB | SKA53_05308 | SKA53_10494 | mazG family protein; COG1694 Predicted pyrophosphatase. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.845 |
| EAQ06479.1 | pyrG | SKA53_05308 | SKA53_07506 | mazG family protein; COG1694 Predicted pyrophosphatase. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.845 |
| EAQ06479.1 | ribB | SKA53_05308 | SKA53_01971 | mazG family protein; COG1694 Predicted pyrophosphatase. | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.846 |
| EAQ06479.1 | thyX | SKA53_05308 | SKA53_07631 | mazG family protein; COG1694 Predicted pyrophosphatase. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.887 |
| EAQ06479.1 | tmk | SKA53_05308 | SKA53_06572 | mazG family protein; COG1694 Predicted pyrophosphatase. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.854 |
| EAQ07534.1 | EAQ06479.1 | SKA53_11893 | SKA53_05308 | Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | mazG family protein; COG1694 Predicted pyrophosphatase. | 0.847 |
| EAQ07534.1 | coaE | SKA53_11893 | SKA53_11903 | Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.903 |
| EAQ07534.1 | pyrG | SKA53_11893 | SKA53_07506 | Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.829 |
| EAQ07534.1 | thyX | SKA53_11893 | SKA53_07631 | Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.815 |