| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ06061.1 | EAQ06399.1 | SKA53_08146 | SKA53_04908 | Hypothetical protein; COG0642 Signal transduction histidine kinase. | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.623 |
| EAQ06061.1 | EAQ06479.1 | SKA53_08146 | SKA53_05308 | Hypothetical protein; COG0642 Signal transduction histidine kinase. | mazG family protein; COG1694 Predicted pyrophosphatase. | 0.883 |
| EAQ06061.1 | EAQ07771.1 | SKA53_08146 | SKA53_13078 | Hypothetical protein; COG0642 Signal transduction histidine kinase. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.950 |
| EAQ06061.1 | ribB | SKA53_08146 | SKA53_01971 | Hypothetical protein; COG0642 Signal transduction histidine kinase. | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.904 |
| EAQ06090.1 | EAQ06479.1 | SKA53_08291 | SKA53_05308 | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | mazG family protein; COG1694 Predicted pyrophosphatase. | 0.866 |
| EAQ06090.1 | pncB | SKA53_08291 | SKA53_10494 | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.890 |
| EAQ06090.1 | surE | SKA53_08291 | SKA53_02561 | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.864 |
| EAQ06399.1 | EAQ06061.1 | SKA53_04908 | SKA53_08146 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Hypothetical protein; COG0642 Signal transduction histidine kinase. | 0.623 |
| EAQ06399.1 | EAQ06479.1 | SKA53_04908 | SKA53_05308 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | mazG family protein; COG1694 Predicted pyrophosphatase. | 0.873 |
| EAQ06399.1 | pyrG | SKA53_04908 | SKA53_07506 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.421 |
| EAQ06479.1 | EAQ06061.1 | SKA53_05308 | SKA53_08146 | mazG family protein; COG1694 Predicted pyrophosphatase. | Hypothetical protein; COG0642 Signal transduction histidine kinase. | 0.883 |
| EAQ06479.1 | EAQ06090.1 | SKA53_05308 | SKA53_08291 | mazG family protein; COG1694 Predicted pyrophosphatase. | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | 0.866 |
| EAQ06479.1 | EAQ06399.1 | SKA53_05308 | SKA53_04908 | mazG family protein; COG1694 Predicted pyrophosphatase. | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.873 |
| EAQ06479.1 | EAQ06494.1 | SKA53_05308 | SKA53_05383 | mazG family protein; COG1694 Predicted pyrophosphatase. | 2''-deoxycytidine 5''-triphosphate deaminase-like protein; COG0717 Deoxycytidine deaminase. | 0.877 |
| EAQ06479.1 | EAQ07771.1 | SKA53_05308 | SKA53_13078 | mazG family protein; COG1694 Predicted pyrophosphatase. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.897 |
| EAQ06479.1 | coaE | SKA53_05308 | SKA53_11903 | mazG family protein; COG1694 Predicted pyrophosphatase. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.865 |
| EAQ06479.1 | pncB | SKA53_05308 | SKA53_10494 | mazG family protein; COG1694 Predicted pyrophosphatase. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.877 |
| EAQ06479.1 | pyrG | SKA53_05308 | SKA53_07506 | mazG family protein; COG1694 Predicted pyrophosphatase. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.873 |
| EAQ06479.1 | ribB | SKA53_05308 | SKA53_01971 | mazG family protein; COG1694 Predicted pyrophosphatase. | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.878 |
| EAQ06479.1 | surE | SKA53_05308 | SKA53_02561 | mazG family protein; COG1694 Predicted pyrophosphatase. | Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.856 |