Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EAQ05277.1Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (925 aa)    
Predicted Functional Partners:
EAQ07326.1
COG0372 Citrate synthase; Belongs to the citrate synthase family.
 
 0.998
EAQ05224.1
COG0538 Isocitrate dehydrogenases.
  
 0.967
EAQ05418.1
COG0538 Isocitrate dehydrogenases.
  
 0.967
fumC
Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.962
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.942
EAQ05231.1
Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.928
EAQ06244.1
Isocitrate lyase family protein; COG2513 PEP phosphonomutase and related enzymes.
  
 0.926
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
  
 0.920
EAQ05559.1
Isocitrate dehydrogenase, NADP-dependent; COG2838 Monomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family.
  
 
 0.902
EAQ07916.1
enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase.
   
 0.897
Your Current Organism:
Yoonia vestfoldensis SKA53
NCBI taxonomy Id: 314232
Other names: Loktanella vestfoldensis SKA53, Y. vestfoldensis SKA53
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