| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05278.1 | EAQ05281.1 | SKA53_05865 | SKA53_05880 | Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily; COG0526 Thiol-disulfide isomerase and thioredoxins. | ABC heme exporter, inner membrane subunit CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | 0.939 |
| EAQ05278.1 | EAQ05283.1 | SKA53_05865 | SKA53_05890 | Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily; COG0526 Thiol-disulfide isomerase and thioredoxins. | Hypothetical protein. | 0.549 |
| EAQ05278.1 | EAQ05436.1 | SKA53_05865 | SKA53_03469 | Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily; COG0526 Thiol-disulfide isomerase and thioredoxins. | COG0785 Cytochrome c biogenesis protein. | 0.713 |
| EAQ05278.1 | EAQ07323.1 | SKA53_05865 | SKA53_02966 | Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily; COG0526 Thiol-disulfide isomerase and thioredoxins. | Cytochrome c-type biogenesis protein CcmF; COG1138 Cytochrome c biogenesis factor. | 0.985 |
| EAQ05278.1 | EAQ07324.1 | SKA53_05865 | SKA53_02971 | Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily; COG0526 Thiol-disulfide isomerase and thioredoxins. | Cytochrome c biogenesis family protein; Possible subunit of a heme lyase. | 0.930 |
| EAQ05278.1 | ccmA | SKA53_05865 | SKA53_05885 | Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily; COG0526 Thiol-disulfide isomerase and thioredoxins. | ABC heme exporter, ATPase subunt CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | 0.841 |
| EAQ05278.1 | ccmC | SKA53_05865 | SKA53_05875 | Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily; COG0526 Thiol-disulfide isomerase and thioredoxins. | ABC heme exporter, inner membrane subunit CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. | 0.976 |
| EAQ05278.1 | ccmE | SKA53_05865 | SKA53_02946 | Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily; COG0526 Thiol-disulfide isomerase and thioredoxins. | Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. | 0.918 |
| EAQ05278.1 | secD | SKA53_05865 | SKA53_05900 | Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily; COG0526 Thiol-disulfide isomerase and thioredoxins. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.506 |
| EAQ05278.1 | secF | SKA53_05865 | SKA53_05895 | Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily; COG0526 Thiol-disulfide isomerase and thioredoxins. | Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.500 |
| EAQ05281.1 | EAQ05278.1 | SKA53_05880 | SKA53_05865 | ABC heme exporter, inner membrane subunit CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily; COG0526 Thiol-disulfide isomerase and thioredoxins. | 0.939 |
| EAQ05281.1 | EAQ05283.1 | SKA53_05880 | SKA53_05890 | ABC heme exporter, inner membrane subunit CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Hypothetical protein. | 0.855 |
| EAQ05281.1 | EAQ07323.1 | SKA53_05880 | SKA53_02966 | ABC heme exporter, inner membrane subunit CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Cytochrome c-type biogenesis protein CcmF; COG1138 Cytochrome c biogenesis factor. | 0.885 |
| EAQ05281.1 | EAQ07324.1 | SKA53_05880 | SKA53_02971 | ABC heme exporter, inner membrane subunit CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Cytochrome c biogenesis family protein; Possible subunit of a heme lyase. | 0.841 |
| EAQ05281.1 | ccmA | SKA53_05880 | SKA53_05885 | ABC heme exporter, inner membrane subunit CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | ABC heme exporter, ATPase subunt CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | 0.999 |
| EAQ05281.1 | ccmC | SKA53_05880 | SKA53_05875 | ABC heme exporter, inner membrane subunit CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | ABC heme exporter, inner membrane subunit CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. | 0.999 |
| EAQ05281.1 | ccmE | SKA53_05880 | SKA53_02946 | ABC heme exporter, inner membrane subunit CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. | 0.951 |
| EAQ05281.1 | secD | SKA53_05880 | SKA53_05900 | ABC heme exporter, inner membrane subunit CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.844 |
| EAQ05281.1 | secF | SKA53_05880 | SKA53_05895 | ABC heme exporter, inner membrane subunit CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.844 |
| EAQ05283.1 | EAQ05278.1 | SKA53_05890 | SKA53_05865 | Hypothetical protein. | Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily; COG0526 Thiol-disulfide isomerase and thioredoxins. | 0.549 |