| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05231.1 | EAQ05298.1 | SKA53_05630 | SKA53_05965 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Putative amino-acid dehydratase; COG1171 Threonine dehydratase. | 0.746 |
| EAQ05231.1 | EAQ06110.1 | SKA53_05630 | SKA53_08391 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG0498 Threonine synthase. | 0.474 |
| EAQ05231.1 | EAQ06531.1 | SKA53_05630 | SKA53_05568 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG0440 Acetolactate synthase, small (regulatory) subunit. | 0.900 |
| EAQ05231.1 | EAQ06946.1 | SKA53_05630 | SKA53_15401 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.501 |
| EAQ05231.1 | EAQ07315.1 | SKA53_05630 | SKA53_02926 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.921 |
| EAQ05231.1 | EAQ07518.1 | SKA53_05630 | SKA53_11813 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. | 0.880 |
| EAQ05231.1 | ilvE | SKA53_05630 | SKA53_10784 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.880 |
| EAQ05231.1 | leuB | SKA53_05630 | SKA53_14936 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.723 |
| EAQ05298.1 | EAQ05231.1 | SKA53_05965 | SKA53_05630 | Putative amino-acid dehydratase; COG1171 Threonine dehydratase. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.746 |
| EAQ05298.1 | EAQ05427.1 | SKA53_05965 | SKA53_03424 | Putative amino-acid dehydratase; COG1171 Threonine dehydratase. | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | 0.704 |
| EAQ05298.1 | EAQ06110.1 | SKA53_05965 | SKA53_08391 | Putative amino-acid dehydratase; COG1171 Threonine dehydratase. | COG0498 Threonine synthase. | 0.820 |
| EAQ05298.1 | EAQ06531.1 | SKA53_05965 | SKA53_05568 | Putative amino-acid dehydratase; COG1171 Threonine dehydratase. | COG0440 Acetolactate synthase, small (regulatory) subunit. | 0.844 |
| EAQ05298.1 | EAQ06946.1 | SKA53_05965 | SKA53_15401 | Putative amino-acid dehydratase; COG1171 Threonine dehydratase. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.766 |
| EAQ05298.1 | EAQ07315.1 | SKA53_05965 | SKA53_02926 | Putative amino-acid dehydratase; COG1171 Threonine dehydratase. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.746 |
| EAQ05298.1 | EAQ07518.1 | SKA53_05965 | SKA53_11813 | Putative amino-acid dehydratase; COG1171 Threonine dehydratase. | COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. | 0.740 |
| EAQ05298.1 | ilvE | SKA53_05965 | SKA53_10784 | Putative amino-acid dehydratase; COG1171 Threonine dehydratase. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.740 |
| EAQ05298.1 | leuB | SKA53_05965 | SKA53_14936 | Putative amino-acid dehydratase; COG1171 Threonine dehydratase. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.769 |
| EAQ05298.1 | trpB | SKA53_05965 | SKA53_01211 | Putative amino-acid dehydratase; COG1171 Threonine dehydratase. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.748 |
| EAQ05427.1 | EAQ05298.1 | SKA53_03424 | SKA53_05965 | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | Putative amino-acid dehydratase; COG1171 Threonine dehydratase. | 0.704 |
| EAQ05427.1 | EAQ06946.1 | SKA53_03424 | SKA53_15401 | COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.926 |