| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05397.1 | glmM | SKA53_00435 | SKA53_07057 | Hypothetical protein; COG1820 N-acetylglucosamine-6-phosphate deacetylase. | Phosphoglucomutase/phosphomannomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.889 |
| EAQ05397.1 | glmS | SKA53_00435 | SKA53_06232 | Hypothetical protein; COG1820 N-acetylglucosamine-6-phosphate deacetylase. | D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.918 |
| EAQ05397.1 | pgi | SKA53_00435 | SKA53_03196 | Hypothetical protein; COG1820 N-acetylglucosamine-6-phosphate deacetylase. | COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.557 |
| EAQ07715.1 | glmM | SKA53_12798 | SKA53_07057 | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Phosphoglucomutase/phosphomannomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.920 |
| EAQ07715.1 | glmS | SKA53_12798 | SKA53_06232 | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.902 |
| EAQ07715.1 | glmU | SKA53_12798 | SKA53_06227 | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.540 |
| EAQ07715.1 | pgi | SKA53_12798 | SKA53_03196 | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.940 |
| EAQ07715.1 | purF | SKA53_12798 | SKA53_02571 | Mannose-6-phosphate isomerase /; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.841 |
| EAQ08212.1 | carA | SKA53_10819 | SKA53_07007 | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | 0.927 |
| EAQ08212.1 | carB | SKA53_10819 | SKA53_09594 | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.976 |
| EAQ08212.1 | glmS | SKA53_10819 | SKA53_06232 | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.967 |
| EAQ08212.1 | glmU | SKA53_10819 | SKA53_06227 | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.526 |
| EAQ08212.1 | purF | SKA53_10819 | SKA53_02571 | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.955 |
| EAQ08212.1 | purQ | SKA53_10819 | SKA53_03444 | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.854 |
| carA | EAQ08212.1 | SKA53_07007 | SKA53_10819 | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 0.927 |
| carA | carB | SKA53_07007 | SKA53_09594 | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.999 |
| carA | glmS | SKA53_07007 | SKA53_06232 | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.879 |
| carA | purF | SKA53_07007 | SKA53_02571 | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.955 |
| carA | purQ | SKA53_07007 | SKA53_03444 | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.932 |
| carB | EAQ08212.1 | SKA53_09594 | SKA53_10819 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 0.976 |