| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ06723.1 | EAQ07907.1 | SKA53_14286 | SKA53_09294 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.977 |
| EAQ06723.1 | EAQ08123.1 | SKA53_14286 | SKA53_10374 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | COG0284 Orotidine-5'-phosphate decarboxylase. | 0.862 |
| EAQ06723.1 | carA | SKA53_14286 | SKA53_07007 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | 0.956 |
| EAQ06723.1 | carB | SKA53_14286 | SKA53_09594 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.967 |
| EAQ06723.1 | pyrB | SKA53_14286 | SKA53_14296 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| EAQ06723.1 | pyrE | SKA53_14286 | SKA53_02601 | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.880 |
| EAQ07907.1 | EAQ06723.1 | SKA53_09294 | SKA53_14286 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.977 |
| EAQ07907.1 | EAQ08123.1 | SKA53_09294 | SKA53_10374 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | COG0284 Orotidine-5'-phosphate decarboxylase. | 0.925 |
| EAQ07907.1 | carA | SKA53_09294 | SKA53_07007 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | 0.937 |
| EAQ07907.1 | carB | SKA53_09294 | SKA53_09594 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.964 |
| EAQ07907.1 | pyrB | SKA53_09294 | SKA53_14296 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.944 |
| EAQ07907.1 | pyrE | SKA53_09294 | SKA53_02601 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.993 |
| EAQ07945.1 | argG | SKA53_09484 | SKA53_11798 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.998 |
| EAQ07945.1 | carA | SKA53_09484 | SKA53_07007 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | 0.994 |
| EAQ07945.1 | carB | SKA53_09484 | SKA53_09594 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.996 |
| EAQ07945.1 | purF | SKA53_09484 | SKA53_02571 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.403 |
| EAQ07945.1 | pyrB | SKA53_09484 | SKA53_14296 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.905 |
| EAQ08123.1 | EAQ06723.1 | SKA53_10374 | SKA53_14286 | COG0284 Orotidine-5'-phosphate decarboxylase. | Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.862 |
| EAQ08123.1 | EAQ07907.1 | SKA53_10374 | SKA53_09294 | COG0284 Orotidine-5'-phosphate decarboxylase. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.925 |
| EAQ08123.1 | carA | SKA53_10374 | SKA53_07007 | COG0284 Orotidine-5'-phosphate decarboxylase. | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | 0.947 |