| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05836.1 | EAQ05837.1 | SKA53_07017 | SKA53_07022 | Transcriptional regulator, GntR family; COG1802 Transcriptional regulators. | Pyrimidine 5'-nucleotidase; COG1011 Predicted hydrolase (HAD superfamily). | 0.545 |
| EAQ05836.1 | EAQ05838.1 | SKA53_07017 | SKA53_07027 | Transcriptional regulator, GntR family; COG1802 Transcriptional regulators. | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.462 |
| EAQ05837.1 | EAQ05836.1 | SKA53_07022 | SKA53_07017 | Pyrimidine 5'-nucleotidase; COG1011 Predicted hydrolase (HAD superfamily). | Transcriptional regulator, GntR family; COG1802 Transcriptional regulators. | 0.545 |
| EAQ05837.1 | EAQ05838.1 | SKA53_07022 | SKA53_07027 | Pyrimidine 5'-nucleotidase; COG1011 Predicted hydrolase (HAD superfamily). | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.776 |
| EAQ05837.1 | EAQ06693.1 | SKA53_07022 | SKA53_14136 | Pyrimidine 5'-nucleotidase; COG1011 Predicted hydrolase (HAD superfamily). | Hypothetical protein. | 0.423 |
| EAQ05837.1 | EAQ07119.1 | SKA53_07022 | SKA53_01946 | Pyrimidine 5'-nucleotidase; COG1011 Predicted hydrolase (HAD superfamily). | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.878 |
| EAQ05837.1 | atpE | SKA53_07022 | SKA53_15041 | Pyrimidine 5'-nucleotidase; COG1011 Predicted hydrolase (HAD superfamily). | ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | 0.423 |
| EAQ05837.1 | guaA | SKA53_07022 | SKA53_04933 | Pyrimidine 5'-nucleotidase; COG1011 Predicted hydrolase (HAD superfamily). | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.781 |
| EAQ05837.1 | guaB | SKA53_07022 | SKA53_03244 | Pyrimidine 5'-nucleotidase; COG1011 Predicted hydrolase (HAD superfamily). | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.756 |
| EAQ05837.1 | nadD | SKA53_07022 | SKA53_14836 | Pyrimidine 5'-nucleotidase; COG1011 Predicted hydrolase (HAD superfamily). | Nicotinic acid mononucleotide adenyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.431 |
| EAQ05837.1 | pncB | SKA53_07022 | SKA53_10494 | Pyrimidine 5'-nucleotidase; COG1011 Predicted hydrolase (HAD superfamily). | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.413 |
| EAQ05837.1 | surE | SKA53_07022 | SKA53_02561 | Pyrimidine 5'-nucleotidase; COG1011 Predicted hydrolase (HAD superfamily). | Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.477 |
| EAQ05838.1 | EAQ05836.1 | SKA53_07027 | SKA53_07017 | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | Transcriptional regulator, GntR family; COG1802 Transcriptional regulators. | 0.462 |
| EAQ05838.1 | EAQ05837.1 | SKA53_07027 | SKA53_07022 | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | Pyrimidine 5'-nucleotidase; COG1011 Predicted hydrolase (HAD superfamily). | 0.776 |
| EAQ06693.1 | EAQ05837.1 | SKA53_14136 | SKA53_07022 | Hypothetical protein. | Pyrimidine 5'-nucleotidase; COG1011 Predicted hydrolase (HAD superfamily). | 0.423 |
| EAQ06693.1 | atpE | SKA53_14136 | SKA53_15041 | Hypothetical protein. | ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | 0.766 |
| EAQ07119.1 | EAQ05837.1 | SKA53_01946 | SKA53_07022 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Pyrimidine 5'-nucleotidase; COG1011 Predicted hydrolase (HAD superfamily). | 0.878 |
| EAQ07119.1 | atpE | SKA53_01946 | SKA53_15041 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | 0.491 |
| EAQ07119.1 | guaA | SKA53_01946 | SKA53_04933 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.667 |
| EAQ07119.1 | guaB | SKA53_01946 | SKA53_03244 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.665 |