| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05231.1 | EAQ05901.1 | SKA53_05630 | SKA53_07346 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | 0.773 |
| EAQ05231.1 | EAQ05902.1 | SKA53_05630 | SKA53_07351 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.918 |
| EAQ05231.1 | EAQ06531.1 | SKA53_05630 | SKA53_05568 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG0440 Acetolactate synthase, small (regulatory) subunit. | 0.920 |
| EAQ05231.1 | EAQ06982.1 | SKA53_05630 | SKA53_01261 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | L-lactate dehydrogenase, putative; COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | 0.773 |
| EAQ05231.1 | EAQ07520.1 | SKA53_05630 | SKA53_11823 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.988 |
| EAQ05231.1 | EAQ07926.1 | SKA53_05630 | SKA53_09389 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.988 |
| EAQ05231.1 | EAQ08094.1 | SKA53_05630 | SKA53_10229 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.916 |
| EAQ05231.1 | guaB | SKA53_05630 | SKA53_03244 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.571 |
| EAQ05231.1 | mdh | SKA53_05630 | SKA53_14541 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.978 |
| EAQ05901.1 | EAQ05231.1 | SKA53_07346 | SKA53_05630 | COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.773 |
| EAQ05901.1 | EAQ05902.1 | SKA53_07346 | SKA53_07351 | COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.885 |
| EAQ05901.1 | EAQ06531.1 | SKA53_07346 | SKA53_05568 | COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | COG0440 Acetolactate synthase, small (regulatory) subunit. | 0.745 |
| EAQ05901.1 | EAQ06982.1 | SKA53_07346 | SKA53_01261 | COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | L-lactate dehydrogenase, putative; COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | 0.769 |
| EAQ05901.1 | EAQ07520.1 | SKA53_07346 | SKA53_11823 | COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.842 |
| EAQ05901.1 | EAQ07926.1 | SKA53_07346 | SKA53_09389 | COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.842 |
| EAQ05901.1 | EAQ08094.1 | SKA53_07346 | SKA53_10229 | COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.779 |
| EAQ05901.1 | guaA | SKA53_07346 | SKA53_04933 | COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.906 |
| EAQ05901.1 | guaB | SKA53_07346 | SKA53_03244 | COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.758 |
| EAQ05901.1 | mdh | SKA53_07346 | SKA53_14541 | COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.765 |
| EAQ05902.1 | EAQ05231.1 | SKA53_07351 | SKA53_05630 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.918 |