| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05231.1 | EAQ05902.1 | SKA53_05630 | SKA53_07351 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.918 |
| EAQ05231.1 | EAQ06790.1 | SKA53_05630 | SKA53_14621 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.843 |
| EAQ05231.1 | EAQ07066.1 | SKA53_05630 | SKA53_01681 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.843 |
| EAQ05231.1 | EAQ07315.1 | SKA53_05630 | SKA53_02926 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.889 |
| EAQ05231.1 | EAQ07326.1 | SKA53_05630 | SKA53_02981 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.982 |
| EAQ05231.1 | EAQ07520.1 | SKA53_05630 | SKA53_11823 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.988 |
| EAQ05231.1 | EAQ07926.1 | SKA53_05630 | SKA53_09389 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.988 |
| EAQ05231.1 | EAQ08094.1 | SKA53_05630 | SKA53_10229 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.916 |
| EAQ05231.1 | mdh | SKA53_05630 | SKA53_14541 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.978 |
| EAQ05231.1 | pckA | SKA53_05630 | SKA53_13138 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.958 |
| EAQ05902.1 | EAQ05231.1 | SKA53_07351 | SKA53_05630 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.918 |
| EAQ05902.1 | EAQ06790.1 | SKA53_07351 | SKA53_14621 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.906 |
| EAQ05902.1 | EAQ07066.1 | SKA53_07351 | SKA53_01681 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.916 |
| EAQ05902.1 | EAQ07315.1 | SKA53_07351 | SKA53_02926 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.889 |
| EAQ05902.1 | EAQ07326.1 | SKA53_07351 | SKA53_02981 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.913 |
| EAQ05902.1 | EAQ07520.1 | SKA53_07351 | SKA53_11823 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.919 |
| EAQ05902.1 | EAQ07926.1 | SKA53_07351 | SKA53_09389 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.919 |
| EAQ05902.1 | EAQ08094.1 | SKA53_07351 | SKA53_10229 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.947 |
| EAQ05902.1 | mdh | SKA53_07351 | SKA53_14541 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.913 |
| EAQ05902.1 | pckA | SKA53_07351 | SKA53_13138 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.888 |
