| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05233.1 | EAQ05534.1 | SKA53_05640 | SKA53_00569 | COG1045 Serine acetyltransferase. | COG1171 Threonine dehydratase. | 0.817 |
| EAQ05233.1 | EAQ05927.1 | SKA53_05640 | SKA53_07476 | COG1045 Serine acetyltransferase. | Probable L-serine dehydratase protein; COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.769 |
| EAQ05233.1 | EAQ07104.1 | SKA53_05640 | SKA53_01871 | COG1045 Serine acetyltransferase. | COG0460 Homoserine dehydrogenase. | 0.845 |
| EAQ05233.1 | EAQ08105.1 | SKA53_05640 | SKA53_10284 | COG1045 Serine acetyltransferase. | COG0560 Phosphoserine phosphatase. | 0.921 |
| EAQ05233.1 | glyA | SKA53_05640 | SKA53_09419 | COG1045 Serine acetyltransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.763 |
| EAQ05233.1 | glyA-2 | SKA53_05640 | SKA53_10924 | COG1045 Serine acetyltransferase. | Hypothetical protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.763 |
| EAQ05233.1 | trpA | SKA53_05640 | SKA53_01266 | COG1045 Serine acetyltransferase. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.820 |
| EAQ05233.1 | trpB | SKA53_05640 | SKA53_01211 | COG1045 Serine acetyltransferase. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.818 |
| EAQ05534.1 | EAQ05233.1 | SKA53_00569 | SKA53_05640 | COG1171 Threonine dehydratase. | COG1045 Serine acetyltransferase. | 0.817 |
| EAQ05534.1 | EAQ05927.1 | SKA53_00569 | SKA53_07476 | COG1171 Threonine dehydratase. | Probable L-serine dehydratase protein; COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.789 |
| EAQ05534.1 | EAQ07101.1 | SKA53_00569 | SKA53_01856 | COG1171 Threonine dehydratase. | COG0346 Lactoylglutathione lyase and related lyases. | 0.750 |
| EAQ05534.1 | EAQ07104.1 | SKA53_00569 | SKA53_01871 | COG1171 Threonine dehydratase. | COG0460 Homoserine dehydrogenase. | 0.829 |
| EAQ05534.1 | EAQ08105.1 | SKA53_00569 | SKA53_10284 | COG1171 Threonine dehydratase. | COG0560 Phosphoserine phosphatase. | 0.755 |
| EAQ05534.1 | glyA | SKA53_00569 | SKA53_09419 | COG1171 Threonine dehydratase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.842 |
| EAQ05534.1 | glyA-2 | SKA53_00569 | SKA53_10924 | COG1171 Threonine dehydratase. | Hypothetical protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.842 |
| EAQ05534.1 | metAA | SKA53_00569 | SKA53_04518 | COG1171 Threonine dehydratase. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.795 |
| EAQ05534.1 | trpA | SKA53_00569 | SKA53_01266 | COG1171 Threonine dehydratase. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.801 |
| EAQ05534.1 | trpB | SKA53_00569 | SKA53_01211 | COG1171 Threonine dehydratase. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.836 |
| EAQ05927.1 | EAQ05233.1 | SKA53_07476 | SKA53_05640 | Probable L-serine dehydratase protein; COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | COG1045 Serine acetyltransferase. | 0.769 |
| EAQ05927.1 | EAQ05534.1 | SKA53_07476 | SKA53_00569 | Probable L-serine dehydratase protein; COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | COG1171 Threonine dehydratase. | 0.789 |