| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ06479.1 | guaA | SKA53_05308 | SKA53_04933 | mazG family protein; COG1694 Predicted pyrophosphatase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.817 |
| EAQ06479.1 | ndk | SKA53_05308 | SKA53_05208 | mazG family protein; COG1694 Predicted pyrophosphatase. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.815 |
| EAQ06479.1 | pyrG | SKA53_05308 | SKA53_07506 | mazG family protein; COG1694 Predicted pyrophosphatase. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.845 |
| argS | guaA | SKA53_05413 | SKA53_04933 | COG0018 Arginyl-tRNA synthetase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.971 |
| argS | pnp | SKA53_05413 | SKA53_12558 | COG0018 Arginyl-tRNA synthetase. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.622 |
| argS | pyrG | SKA53_05413 | SKA53_07506 | COG0018 Arginyl-tRNA synthetase. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.883 |
| argS | rho | SKA53_05413 | SKA53_11883 | COG0018 Arginyl-tRNA synthetase. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.472 |
| argS | rpoB | SKA53_05413 | SKA53_13273 | COG0018 Arginyl-tRNA synthetase. | DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.708 |
| argS | rpoC | SKA53_05413 | SKA53_13278 | COG0018 Arginyl-tRNA synthetase. | DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.782 |
| argS | rpsB | SKA53_05413 | SKA53_04723 | COG0018 Arginyl-tRNA synthetase. | COG0052 Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.550 |
| guaA | EAQ06479.1 | SKA53_04933 | SKA53_05308 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | mazG family protein; COG1694 Predicted pyrophosphatase. | 0.817 |
| guaA | argS | SKA53_04933 | SKA53_05413 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | COG0018 Arginyl-tRNA synthetase. | 0.971 |
| guaA | ndk | SKA53_04933 | SKA53_05208 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.566 |
| guaA | pnp | SKA53_04933 | SKA53_12558 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.859 |
| guaA | pyrG | SKA53_04933 | SKA53_07506 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.965 |
| guaA | rho | SKA53_04933 | SKA53_11883 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.450 |
| guaA | rplY | SKA53_04933 | SKA53_01246 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.650 |
| guaA | rpoB | SKA53_04933 | SKA53_13273 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.916 |
| guaA | rpoC | SKA53_04933 | SKA53_13278 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.915 |
| guaA | rpsB | SKA53_04933 | SKA53_04723 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | COG0052 Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.714 |