| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05943.1 | EAQ05944.1 | SKA53_07556 | SKA53_07561 | COG0518 GMP synthase - Glutamine amidotransferase domain. | COG0174 Glutamine synthetase. | 0.857 |
| EAQ05943.1 | EAQ05945.1 | SKA53_07556 | SKA53_07566 | COG0518 GMP synthase - Glutamine amidotransferase domain. | Hypothetical protein; COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.866 |
| EAQ05943.1 | EAQ06399.1 | SKA53_07556 | SKA53_04908 | COG0518 GMP synthase - Glutamine amidotransferase domain. | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.851 |
| EAQ05943.1 | EAQ07525.1 | SKA53_07556 | SKA53_11848 | COG0518 GMP synthase - Glutamine amidotransferase domain. | Putative deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.820 |
| EAQ05943.1 | EAQ07905.1 | SKA53_07556 | SKA53_09284 | COG0518 GMP synthase - Glutamine amidotransferase domain. | COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.820 |
| EAQ05943.1 | gmk | SKA53_07556 | SKA53_04778 | COG0518 GMP synthase - Glutamine amidotransferase domain. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.847 |
| EAQ05943.1 | gpt | SKA53_07556 | SKA53_03051 | COG0518 GMP synthase - Glutamine amidotransferase domain. | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.815 |
| EAQ05943.1 | guaA | SKA53_07556 | SKA53_04933 | COG0518 GMP synthase - Glutamine amidotransferase domain. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.861 |
| EAQ05943.1 | guaB | SKA53_07556 | SKA53_03244 | COG0518 GMP synthase - Glutamine amidotransferase domain. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.958 |
| EAQ05943.1 | surE | SKA53_07556 | SKA53_02561 | COG0518 GMP synthase - Glutamine amidotransferase domain. | Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.844 |
| EAQ05944.1 | EAQ05943.1 | SKA53_07561 | SKA53_07556 | COG0174 Glutamine synthetase. | COG0518 GMP synthase - Glutamine amidotransferase domain. | 0.857 |
| EAQ05944.1 | EAQ05945.1 | SKA53_07561 | SKA53_07566 | COG0174 Glutamine synthetase. | Hypothetical protein; COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.956 |
| EAQ05944.1 | guaA | SKA53_07561 | SKA53_04933 | COG0174 Glutamine synthetase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.558 |
| EAQ05945.1 | EAQ05943.1 | SKA53_07566 | SKA53_07556 | Hypothetical protein; COG0665 Glycine/D-amino acid oxidases (deaminating). | COG0518 GMP synthase - Glutamine amidotransferase domain. | 0.866 |
| EAQ05945.1 | EAQ05944.1 | SKA53_07566 | SKA53_07561 | Hypothetical protein; COG0665 Glycine/D-amino acid oxidases (deaminating). | COG0174 Glutamine synthetase. | 0.956 |
| EAQ06399.1 | EAQ05943.1 | SKA53_04908 | SKA53_07556 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | COG0518 GMP synthase - Glutamine amidotransferase domain. | 0.851 |
| EAQ06399.1 | EAQ07525.1 | SKA53_04908 | SKA53_11848 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Putative deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.816 |
| EAQ06399.1 | EAQ07905.1 | SKA53_04908 | SKA53_09284 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.815 |
| EAQ06399.1 | gmk | SKA53_04908 | SKA53_04778 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.913 |
| EAQ06399.1 | gpt | SKA53_04908 | SKA53_03051 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.815 |