| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05212.1 | EAQ05421.1 | SKA53_03314 | SKA53_03394 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. | 0.467 |
| EAQ05212.1 | EAQ06035.1 | SKA53_03314 | SKA53_08016 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | COG0404 Glycine cleavage system T protein (aminomethyltransferase); Belongs to the GcvT family. | 0.901 |
| EAQ05212.1 | EAQ06946.1 | SKA53_03314 | SKA53_15401 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.995 |
| EAQ05212.1 | EAQ08212.1 | SKA53_03314 | SKA53_10819 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 0.556 |
| EAQ05212.1 | fhs | SKA53_03314 | SKA53_08541 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | Formate--tetrahydrofolate ligase; COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | 0.493 |
| EAQ05212.1 | fmt | SKA53_03314 | SKA53_09969 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.445 |
| EAQ05212.1 | folD | SKA53_03314 | SKA53_08536 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | folD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.882 |
| EAQ05212.1 | purH | SKA53_03314 | SKA53_12688 | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.468 |
| EAQ05421.1 | EAQ05212.1 | SKA53_03394 | SKA53_03314 | COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | 0.467 |
| EAQ05421.1 | EAQ06035.1 | SKA53_03394 | SKA53_08016 | COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. | COG0404 Glycine cleavage system T protein (aminomethyltransferase); Belongs to the GcvT family. | 0.881 |
| EAQ05421.1 | EAQ06946.1 | SKA53_03394 | SKA53_15401 | COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.871 |
| EAQ05421.1 | EAQ08212.1 | SKA53_03394 | SKA53_10819 | COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. | Glutamine-pyruvate aminotransferase; COG0067 Glutamate synthase domain 1. | 0.432 |
| EAQ05421.1 | fhs | SKA53_03394 | SKA53_08541 | COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. | Formate--tetrahydrofolate ligase; COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | 0.962 |
| EAQ05421.1 | fmt | SKA53_03394 | SKA53_09969 | COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.914 |
| EAQ05421.1 | folD | SKA53_03394 | SKA53_08536 | COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. | folD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.980 |
| EAQ05421.1 | purH | SKA53_03394 | SKA53_12688 | COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.999 |
| EAQ06035.1 | EAQ05212.1 | SKA53_08016 | SKA53_03314 | COG0404 Glycine cleavage system T protein (aminomethyltransferase); Belongs to the GcvT family. | MetF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | 0.901 |
| EAQ06035.1 | EAQ05421.1 | SKA53_08016 | SKA53_03394 | COG0404 Glycine cleavage system T protein (aminomethyltransferase); Belongs to the GcvT family. | COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. | 0.881 |
| EAQ06035.1 | EAQ06946.1 | SKA53_08016 | SKA53_15401 | COG0404 Glycine cleavage system T protein (aminomethyltransferase); Belongs to the GcvT family. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.889 |
| EAQ06035.1 | EAQ07081.1 | SKA53_08016 | SKA53_01756 | COG0404 Glycine cleavage system T protein (aminomethyltransferase); Belongs to the GcvT family. | Hypothetical protein. | 0.874 |