| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05689.1 | EAQ06090.1 | SKA53_06282 | SKA53_08291 | NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | 0.815 |
| EAQ05689.1 | EAQ06396.1 | SKA53_06282 | SKA53_04893 | NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Competence/damage-inducible protein CinA domain protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | 0.416 |
| EAQ05689.1 | EAQ06479.1 | SKA53_06282 | SKA53_05308 | NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | mazG family protein; COG1694 Predicted pyrophosphatase. | 0.817 |
| EAQ05689.1 | nadD | SKA53_06282 | SKA53_14836 | NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Nicotinic acid mononucleotide adenyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.815 |
| EAQ05689.1 | nadE | SKA53_06282 | SKA53_08994 | NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.886 |
| EAQ05689.1 | nadK | SKA53_06282 | SKA53_09409 | NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.911 |
| EAQ05689.1 | pntA | SKA53_06282 | SKA53_06287 | NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | NAD(P) transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | 0.999 |
| EAQ06090.1 | EAQ05689.1 | SKA53_08291 | SKA53_06282 | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.815 |
| EAQ06090.1 | EAQ06396.1 | SKA53_08291 | SKA53_04893 | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | Competence/damage-inducible protein CinA domain protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | 0.820 |
| EAQ06090.1 | EAQ06479.1 | SKA53_08291 | SKA53_05308 | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | mazG family protein; COG1694 Predicted pyrophosphatase. | 0.831 |
| EAQ06090.1 | EAQ07905.1 | SKA53_08291 | SKA53_09284 | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.822 |
| EAQ06090.1 | nadD | SKA53_08291 | SKA53_14836 | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | Nicotinic acid mononucleotide adenyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.823 |
| EAQ06090.1 | nadE | SKA53_08291 | SKA53_08994 | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.828 |
| EAQ06090.1 | nadK | SKA53_08291 | SKA53_09409 | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.815 |
| EAQ06090.1 | pncB | SKA53_08291 | SKA53_10494 | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.834 |
| EAQ06090.1 | pntA | SKA53_08291 | SKA53_06287 | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | NAD(P) transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | 0.815 |
| EAQ06090.1 | surE | SKA53_08291 | SKA53_02561 | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.832 |
| EAQ06396.1 | EAQ05689.1 | SKA53_04893 | SKA53_06282 | Competence/damage-inducible protein CinA domain protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.416 |
| EAQ06396.1 | EAQ06090.1 | SKA53_04893 | SKA53_08291 | Competence/damage-inducible protein CinA domain protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | Hydrolase, NUDIX family; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. | 0.820 |
| EAQ06396.1 | EAQ06479.1 | SKA53_04893 | SKA53_05308 | Competence/damage-inducible protein CinA domain protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | mazG family protein; COG1694 Predicted pyrophosphatase. | 0.815 |