| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ05487.1 | EAQ06101.1 | SKA53_03724 | SKA53_08346 | Hypothetical protein; COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase. | Phosphoenolpyruvate-protein phosphotransferase; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | 0.808 |
| EAQ06098.1 | EAQ06099.1 | SKA53_08331 | SKA53_08336 | COG5319 Uncharacterized protein conserved in bacteria. | Oxidoreductase, short-chain dehydrogenase/reductase family; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.855 |
| EAQ06098.1 | EAQ06100.1 | SKA53_08331 | SKA53_08341 | COG5319 Uncharacterized protein conserved in bacteria. | Aspartate kinase, monofunctional class; COG0527 Aspartokinases; Belongs to the aspartokinase family. | 0.716 |
| EAQ06098.1 | EAQ06101.1 | SKA53_08331 | SKA53_08346 | COG5319 Uncharacterized protein conserved in bacteria. | Phosphoenolpyruvate-protein phosphotransferase; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | 0.690 |
| EAQ06099.1 | EAQ06098.1 | SKA53_08336 | SKA53_08331 | Oxidoreductase, short-chain dehydrogenase/reductase family; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | COG5319 Uncharacterized protein conserved in bacteria. | 0.855 |
| EAQ06099.1 | EAQ06100.1 | SKA53_08336 | SKA53_08341 | Oxidoreductase, short-chain dehydrogenase/reductase family; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Aspartate kinase, monofunctional class; COG0527 Aspartokinases; Belongs to the aspartokinase family. | 0.659 |
| EAQ06099.1 | EAQ06101.1 | SKA53_08336 | SKA53_08346 | Oxidoreductase, short-chain dehydrogenase/reductase family; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Phosphoenolpyruvate-protein phosphotransferase; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | 0.585 |
| EAQ06099.1 | EAQ06946.1 | SKA53_08336 | SKA53_15401 | Oxidoreductase, short-chain dehydrogenase/reductase family; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.489 |
| EAQ06100.1 | EAQ06098.1 | SKA53_08341 | SKA53_08331 | Aspartate kinase, monofunctional class; COG0527 Aspartokinases; Belongs to the aspartokinase family. | COG5319 Uncharacterized protein conserved in bacteria. | 0.716 |
| EAQ06100.1 | EAQ06099.1 | SKA53_08341 | SKA53_08336 | Aspartate kinase, monofunctional class; COG0527 Aspartokinases; Belongs to the aspartokinase family. | Oxidoreductase, short-chain dehydrogenase/reductase family; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.659 |
| EAQ06100.1 | EAQ06101.1 | SKA53_08341 | SKA53_08346 | Aspartate kinase, monofunctional class; COG0527 Aspartokinases; Belongs to the aspartokinase family. | Phosphoenolpyruvate-protein phosphotransferase; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | 0.782 |
| EAQ06100.1 | EAQ06946.1 | SKA53_08341 | SKA53_15401 | Aspartate kinase, monofunctional class; COG0527 Aspartokinases; Belongs to the aspartokinase family. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.906 |
| EAQ06101.1 | EAQ05487.1 | SKA53_08346 | SKA53_03724 | Phosphoenolpyruvate-protein phosphotransferase; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | Hypothetical protein; COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase. | 0.808 |
| EAQ06101.1 | EAQ06098.1 | SKA53_08346 | SKA53_08331 | Phosphoenolpyruvate-protein phosphotransferase; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | COG5319 Uncharacterized protein conserved in bacteria. | 0.690 |
| EAQ06101.1 | EAQ06099.1 | SKA53_08346 | SKA53_08336 | Phosphoenolpyruvate-protein phosphotransferase; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | Oxidoreductase, short-chain dehydrogenase/reductase family; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.585 |
| EAQ06101.1 | EAQ06100.1 | SKA53_08346 | SKA53_08341 | Phosphoenolpyruvate-protein phosphotransferase; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | Aspartate kinase, monofunctional class; COG0527 Aspartokinases; Belongs to the aspartokinase family. | 0.782 |
| EAQ06101.1 | EAQ06946.1 | SKA53_08346 | SKA53_15401 | Phosphoenolpyruvate-protein phosphotransferase; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.780 |
| EAQ06101.1 | EAQ07266.1 | SKA53_08346 | SKA53_02681 | Phosphoenolpyruvate-protein phosphotransferase; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | Siroheme synthetase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.508 |
| EAQ06101.1 | EAQ07469.1 | SKA53_08346 | SKA53_11568 | Phosphoenolpyruvate-protein phosphotransferase; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | PTS IIA-like nitrogen-regulatory protein PtsN; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). | 0.806 |
| EAQ06101.1 | EAQ07788.1 | SKA53_08346 | SKA53_13163 | Phosphoenolpyruvate-protein phosphotransferase; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | PTS system IIA component, Man family; COG2893 Phosphotransferase system, mannose/fructose-specific component IIA. | 0.695 |