| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ06104.1 | apt | SKA53_08361 | SKA53_08371 | COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.831 |
| EAQ06104.1 | mtnP | SKA53_08361 | SKA53_08366 | COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family. | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.796 |
| EAQ06399.1 | EAQ07831.1 | SKA53_04908 | SKA53_08914 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B. | 0.815 |
| EAQ06399.1 | EAQ07921.1 | SKA53_04908 | SKA53_09364 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | COG1816 Adenosine deaminase. | 0.786 |
| EAQ06399.1 | amn | SKA53_04908 | SKA53_12138 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | 0.473 |
| EAQ06399.1 | apt | SKA53_04908 | SKA53_08371 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.723 |
| EAQ06399.1 | deoD | SKA53_04908 | SKA53_14611 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | COG0813 Purine-nucleoside phosphorylase. | 0.916 |
| EAQ06399.1 | mtnP | SKA53_04908 | SKA53_08366 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.807 |
| EAQ06399.1 | surE | SKA53_04908 | SKA53_02561 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.846 |
| EAQ07461.1 | EAQ07921.1 | SKA53_11528 | SKA53_09364 | Putative S-adenosyl L-homocystein hydrolase; COG1896 Predicted hydrolases of HD superfamily. | COG1816 Adenosine deaminase. | 0.815 |
| EAQ07461.1 | deoD | SKA53_11528 | SKA53_14611 | Putative S-adenosyl L-homocystein hydrolase; COG1896 Predicted hydrolases of HD superfamily. | COG0813 Purine-nucleoside phosphorylase. | 0.815 |
| EAQ07461.1 | mtnP | SKA53_11528 | SKA53_08366 | Putative S-adenosyl L-homocystein hydrolase; COG1896 Predicted hydrolases of HD superfamily. | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.743 |
| EAQ07461.1 | surE | SKA53_11528 | SKA53_02561 | Putative S-adenosyl L-homocystein hydrolase; COG1896 Predicted hydrolases of HD superfamily. | Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.837 |
| EAQ07831.1 | EAQ06399.1 | SKA53_08914 | SKA53_04908 | COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B. | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.815 |
| EAQ07831.1 | EAQ07921.1 | SKA53_08914 | SKA53_09364 | COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B. | COG1816 Adenosine deaminase. | 0.766 |
| EAQ07831.1 | apt | SKA53_08914 | SKA53_08371 | COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.467 |
| EAQ07831.1 | deoD | SKA53_08914 | SKA53_14611 | COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B. | COG0813 Purine-nucleoside phosphorylase. | 0.815 |
| EAQ07831.1 | mtnP | SKA53_08914 | SKA53_08366 | COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B. | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.740 |
| EAQ07921.1 | EAQ06399.1 | SKA53_09364 | SKA53_04908 | COG1816 Adenosine deaminase. | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.786 |
| EAQ07921.1 | EAQ07461.1 | SKA53_09364 | SKA53_11528 | COG1816 Adenosine deaminase. | Putative S-adenosyl L-homocystein hydrolase; COG1896 Predicted hydrolases of HD superfamily. | 0.815 |