Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EAQ06122.1COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit. (212 aa)    
Predicted Functional Partners:
EAQ06121.1
COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit.
 0.999
EAQ05476.1
COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit.
 0.998
EAQ05477.1
COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit.
 0.998
EAQ07916.1
enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase.
  
 0.854
EAQ05672.1
hydroxymethylglutaryl-CoA lyase; COG0119 Isopropylmalate/homocitrate/citramalate synthases.
  
 
  0.790
EAQ07790.1
COG1250 3-hydroxyacyl-CoA dehydrogenase.
  
 
 0.759
EAQ05692.1
COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
   
  0.738
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.715
EAQ05231.1
Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.686
EAQ06069.1
COG1454 Alcohol dehydrogenase, class IV.
  
 
 0.586
Your Current Organism:
Yoonia vestfoldensis SKA53
NCBI taxonomy Id: 314232
Other names: Loktanella vestfoldensis SKA53, Y. vestfoldensis SKA53
Server load: medium (52%) [HD]